Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil.

Source:http://linkedlifedata.com/resource/pubmed/id/9380737

Proc. Natl. Acad. Sci. U.S.A. 1997 Sep 30 94 20 10931-6

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PMID
9380737