Meconium aspiration syndrome remains a common cause of respiratory failure in neonates. The acute effects of meconium aspiration are inactivation of lung surfactant in vivo and in vitro. This study investigated the delayed effects of meconium on alveolar surfactant phospholipids and protein levels in spontaneously breathing animals.
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Thomas Jefferson University and Hospital, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA.
