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pubmed-article:9374341pubmed:abstractTextSurgical procedures usually involve the administration of narcotic drugs as anesthetics or adjuvants. To reverse the effects of anesthesia, opioid antagonists such as naloxone are commonly used. Due to its short lasting effects, patients receiving naloxone must be monitored carefully. Nalmefene, a pure opiate antagonist with a longer duration of action than naloxone, has shown promise in the reversal of opioid anesthesia.lld:pubmed
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pubmed-article:9374341pubmed:articleTitleLonger occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system.lld:pubmed
pubmed-article:9374341pubmed:affiliationDivision of Nuclear Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205-2179, USA.lld:pubmed
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