| pubmed-article:9372506 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9372506 | lifeskim:mentions | umls-concept:C0026769 | lld:lifeskim |
| pubmed-article:9372506 | lifeskim:mentions | umls-concept:C1326120 | lld:lifeskim |
| pubmed-article:9372506 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9372506 | pubmed:dateCreated | 1997-12-22 | lld:pubmed |
| pubmed-article:9372506 | pubmed:abstractText | Activated T cells are able to stimulate proliferation in resting T cells through an antigen non-specific mechanism. The in vivo usefulness of this T cell-T cell activation is unclear, but it may serve to amplify immune responses. T cell-T cell activation could be involved in the well-documented occurrence of multiple sclerosis (MS) exacerbations following viral infections. Excessive activation via this pathway could also be a factor in the etiology of MS. We tested the hypothesis that excessive T cell-T cell activation occurs in MS patients using in vitro proliferation assays comparing T cells from MS patients to T cells from controls. When tested as responder cells, T cells from MS patients proliferated slightly less after stimulation with previously activated cells than T cells from controls. When tested as stimulator cells, activated cells from MS patients stimulated slightly more non-specific proliferation than activated cells from controls. Neither of these differences were statistically significant. We conclude that T cell proliferation in response to activated T cells is similar in MS and controls. | lld:pubmed |
| pubmed-article:9372506 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9372506 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9372506 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9372506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9372506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9372506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9372506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9372506 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9372506 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9372506 | pubmed:issn | 1352-4585 | lld:pubmed |
| pubmed-article:9372506 | pubmed:author | pubmed-author:WolinskyJ SJS | lld:pubmed |
| pubmed-article:9372506 | pubmed:author | pubmed-author:KermanR HRH | lld:pubmed |
| pubmed-article:9372506 | pubmed:author | pubmed-author:LindseyJ WJW | lld:pubmed |
| pubmed-article:9372506 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9372506 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:9372506 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9372506 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9372506 | pubmed:pagination | 238-42 | lld:pubmed |
| pubmed-article:9372506 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:meshHeading | pubmed-meshheading:9372506-... | lld:pubmed |
| pubmed-article:9372506 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9372506 | pubmed:articleTitle | T cell-T cell activation in multiple sclerosis. | lld:pubmed |
| pubmed-article:9372506 | pubmed:affiliation | Department of Neurology, University of Texas-Houston Medical School 77030, USA. | lld:pubmed |
| pubmed-article:9372506 | pubmed:publicationType | Journal Article | lld:pubmed |
