| pubmed-article:9366059 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C0036111 | lld:lifeskim |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C0039005 | lld:lifeskim |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C0022378 | lld:lifeskim |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C0061851 | lld:lifeskim |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C1704353 | lld:lifeskim |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C0815327 | lld:lifeskim |
| pubmed-article:9366059 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:9366059 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9366059 | pubmed:dateCreated | 1998-1-14 | lld:pubmed |
| pubmed-article:9366059 | pubmed:abstractText | Two major pathophysiological mechanisms explaining the diarrhoea induced by Salmonella typhimurium have been suggested to be: (a) invasion of the intestine by the bacteria, and (b) an enterotoxin resembling Vibrio cholerae toxin. Cholera toxin is a potent secretagogue in pig small intestine and induces secretion partly by activating 5-hydroxytryptamine receptors, following release of 5-hydroxytryptamine. Ondansetron is a selective 5-hydroxytryptamine-3 receptor antagonist, which reduces the cholera toxin-evoked fluid accumulation in pig jejunum. The aim of this study was to investigate the effect of ondansetron on Salmonella typhimurium-induced fluid accumulation in ligated loops of pig jejunum in vivo. 10(10) colony-forming units of the bacteria was injected into loops and incubated for 8 hr. 200 mg x kg-1 ondansetron given subcutaneously reduced the Salmonella typhimurium-induced fluid accumulation by about 40%. This results suggests the involvement of 5-hydroxytryptamine and 5-hydroxytryptamine-3 receptors in Salmonella typhimurium-induced diarrhoea. | lld:pubmed |
| pubmed-article:9366059 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9366059 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9366059 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9366059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9366059 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9366059 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9366059 | pubmed:issn | 1096-4940 | lld:pubmed |
| pubmed-article:9366059 | pubmed:author | pubmed-author:SkadhaugeEE | lld:pubmed |
| pubmed-article:9366059 | pubmed:author | pubmed-author:JensenG MGM | lld:pubmed |
| pubmed-article:9366059 | pubmed:author | pubmed-author:NielsenC GCG | lld:pubmed |
| pubmed-article:9366059 | pubmed:author | pubmed-author:HansenM BMB | lld:pubmed |
| pubmed-article:9366059 | pubmed:author | pubmed-author:OlsenJ EJE | lld:pubmed |
| pubmed-article:9366059 | pubmed:author | pubmed-author:GrøndahlM LML | lld:pubmed |
| pubmed-article:9366059 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9366059 | pubmed:volume | 118 | lld:pubmed |
| pubmed-article:9366059 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9366059 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9366059 | pubmed:pagination | 297-9 | lld:pubmed |
| pubmed-article:9366059 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9366059 | pubmed:meshHeading | pubmed-meshheading:9366059-... | lld:pubmed |
| pubmed-article:9366059 | pubmed:meshHeading | pubmed-meshheading:9366059-... | lld:pubmed |
| pubmed-article:9366059 | pubmed:meshHeading | pubmed-meshheading:9366059-... | lld:pubmed |
| pubmed-article:9366059 | pubmed:meshHeading | pubmed-meshheading:9366059-... | lld:pubmed |
| pubmed-article:9366059 | pubmed:meshHeading | pubmed-meshheading:9366059-... | lld:pubmed |
| pubmed-article:9366059 | pubmed:meshHeading | pubmed-meshheading:9366059-... | lld:pubmed |
| pubmed-article:9366059 | pubmed:meshHeading | pubmed-meshheading:9366059-... | lld:pubmed |
| pubmed-article:9366059 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9366059 | pubmed:articleTitle | Effect of ondansetron on Salmonella typhimurium-induced net fluid accumulation in the pig jejunum in vivo. | lld:pubmed |
| pubmed-article:9366059 | pubmed:affiliation | Department of Physiology and Anatomy, Royal Veterinary and Agricultural University, Frederiksberg, Denmark. | lld:pubmed |
| pubmed-article:9366059 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9366059 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:9366059 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9366059 | lld:pubmed |
