pubmed-article:9365071 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9365071 | lifeskim:mentions | umls-concept:C0029434 | lld:lifeskim |
pubmed-article:9365071 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
pubmed-article:9365071 | lifeskim:mentions | umls-concept:C0012544 | lld:lifeskim |
pubmed-article:9365071 | lifeskim:mentions | umls-concept:C2267018 | lld:lifeskim |
pubmed-article:9365071 | lifeskim:mentions | umls-concept:C0285778 | lld:lifeskim |
pubmed-article:9365071 | pubmed:issue | 10 | lld:pubmed |
pubmed-article:9365071 | pubmed:dateCreated | 1997-12-29 | lld:pubmed |
pubmed-article:9365071 | pubmed:abstractText | Osteoporosis is an important feature of osteogenesis imperfecta (OI). So far, no effective medical treatment is available. We treated three boys with severe OI type III and vertebral deformities for 5-7 years with continuous oral administration of the bisphosphonate, olpadronate. Treatment resulted in a decreased number of bone fractures, an increased calcification of the long bones and an amelioration of vertebral shape. No side-effects were encountered. CONCLUSION: These preliminary but long-term observations suggest that the bisphosphonate olpadronate may be a useful treatment for patients with OI and vertebral fractures. Bisphosphonates may be promising drugs for children with OI. | lld:pubmed |
pubmed-article:9365071 | pubmed:language | eng | lld:pubmed |
pubmed-article:9365071 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9365071 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9365071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9365071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9365071 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9365071 | pubmed:month | Oct | lld:pubmed |
pubmed-article:9365071 | pubmed:issn | 0340-6199 | lld:pubmed |
pubmed-article:9365071 | pubmed:author | pubmed-author:PapapoulosS... | lld:pubmed |
pubmed-article:9365071 | pubmed:author | pubmed-author:MassaG GGG | lld:pubmed |
pubmed-article:9365071 | pubmed:author | pubmed-author:van de... | lld:pubmed |
pubmed-article:9365071 | pubmed:author | pubmed-author:Maaswinkel-Mo... | lld:pubmed |
pubmed-article:9365071 | pubmed:author | pubmed-author:Landsmeer-Bek... | lld:pubmed |
pubmed-article:9365071 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9365071 | pubmed:volume | 156 | lld:pubmed |
pubmed-article:9365071 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9365071 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9365071 | pubmed:pagination | 792-4 | lld:pubmed |
pubmed-article:9365071 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:meshHeading | pubmed-meshheading:9365071-... | lld:pubmed |
pubmed-article:9365071 | pubmed:year | 1997 | lld:pubmed |
pubmed-article:9365071 | pubmed:articleTitle | Treatment of osteogenesis imperfecta with the bisphosphonate olpadronate (dimethylaminohydroxypropylidene bisphosphonate). | lld:pubmed |
pubmed-article:9365071 | pubmed:affiliation | Department of Paediatrics, University Hospital Leiden, The Netherlands. | lld:pubmed |
pubmed-article:9365071 | pubmed:publicationType | Journal Article | lld:pubmed |
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