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pubmed-article:9343104pubmed:dateCreated1997-11-28lld:pubmed
pubmed-article:9343104pubmed:abstractTextThe use of a charged-particle microbeam provides a unique opportunity to control precisely, the number of particles traversing individual cells and the localization of dose within the cell. The accuracy of 'aiming' and of delivering a precise number of particles crucially depends on the design and implementation of the collimation and detection system. This report describes the methods available for collimating and detecting energetic particles in the context of a radiobiological microbeam. The arrangement developed at the Gray Laboratory uses either a 'V'-groove or a thick-walled glass capillary to achieve 2-5 microns spatial resolution. The particle detection system uses an 18 microns thick transmission scintillator and photomultiplier tube to detect particles with > 99% efficiency.lld:pubmed
pubmed-article:9343104pubmed:languageenglld:pubmed
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pubmed-article:9343104pubmed:issn0955-3002lld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:MichaelB DBDlld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:VojnovicBBlld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:PriseK MKMlld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:BowenA DADlld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:WattsS JSJlld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:SchettiniMMlld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:FolkardMMlld:pubmed
pubmed-article:9343104pubmed:authorpubmed-author:HollisK JKJlld:pubmed
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pubmed-article:9343104pubmed:volume72lld:pubmed
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pubmed-article:9343104pubmed:authorsCompleteYlld:pubmed
pubmed-article:9343104pubmed:pagination387-95lld:pubmed
pubmed-article:9343104pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:9343104pubmed:year1997lld:pubmed
pubmed-article:9343104pubmed:articleTitleA charged-particle microbeam: II. A single-particle micro-collimation and detection system.lld:pubmed
pubmed-article:9343104pubmed:affiliationGray Laboratory Cancer Research Trust, Mount Vernon Hospital, Northwood, Middlesex, UK.lld:pubmed
pubmed-article:9343104pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9343104pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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