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pubmed-article:9330014pubmed:abstractTextStudies performed with schizophrenic adults who were resistant to classical neuroleptics showed improvement in 30% of the patients when treated with clozapine. Very early onset schizophrenic patients benefit only partially from conventional antipsychotics and are at increased risk of developing extrapyramidal symptoms; clozapine may offer an alternative treatment for these patients.lld:pubmed
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pubmed-article:9330014pubmed:articleTitleAn open trial of clozapine in neuroleptic-resistant childhood-onset schizophrenia.lld:pubmed
pubmed-article:9330014pubmed:affiliationChild and Adolescent Outpatient Clinic, Ness Ziona Mental Health Center, Israel.lld:pubmed
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