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pubmed-article:9305473pubmed:abstractTextUlcerative colitis is predominantly a disease of non-smokers, and transdermal nicotine is therapeutic but often results in side-effects. Administration of nicotine as a liquid rectal enema results in less systemic nicotine absorption.lld:pubmed
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pubmed-article:9305473pubmed:articleTitleNicotine tartrate liquid enemas for mildly to moderately active left-sided ulcerative colitis unresponsive to first-line therapy: a pilot study.lld:pubmed
pubmed-article:9305473pubmed:affiliationInflammatory Bowel Disease Clinic, Mayo Clinic, Rochester, Minnesota 55905, USA.lld:pubmed
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