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pubmed-article:9304232pubmed:abstractTextChronic administration of dopaminomimetic drugs, levodopa before all, to patients with Parkinson's disease (PD) is accompanied with numerous complications. Psychiatric complications are not only frequent, but also difficult to manage. Reduction of the daily dose or complete discontinuation of dopaminomimetic therapy and usage of conventional neuroleptic drugs may relieve the psychotic symptoms, but both these approaches are associated with unacceptable deterioration of motor symptoms. The aim of the study is to present our experience in the treatment of levodopa-induced psychoses by clozapine in patients with PD. Clozapine is a non-typical antipsychotic drug with low potential fr inducing extrapyramidal symptoms.lld:pubmed
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pubmed-article:9304232pubmed:articleTitle[Clozapine in the treatment of adverse psychiatric manifestations of long-term therapy with levodopa].lld:pubmed
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