| pubmed-article:9291131 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C0009498 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C0016006 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C0009511 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C0056207 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C1705248 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C1548799 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C1524073 | lld:lifeskim |
| pubmed-article:9291131 | lifeskim:mentions | umls-concept:C0449432 | lld:lifeskim |
| pubmed-article:9291131 | pubmed:dateCreated | 1997-9-29 | lld:pubmed |
| pubmed-article:9291131 | pubmed:abstractText | Using a microtitre plate assay, direct binding between complement factors I and H was demonstrated, and ligand blotting indicated that factor H interacts with the heavy chain of factor I. Similarly, direct C3(NH3)-factor I and C3(NH3)-factor H binding was characterized [where C3(NH3) is a form of C3 that is cleaved by factor I in the presence of factor H]. Both factor H and factor I interacted with both chains of C3(NH3) in ligand blotting. Binding reactions between all three pairs of components were highly dependent on ionic strength, and showed similar pH optima. Binding assays with all three components present led to the following conclusions. (a) Binding sites for C3(NH3) and factor I on factor H do not overlap, and binding of factor I and C3(NH3) to soluble factor H promotes the weak factor I-C3(NH3) interaction. (b) Anomalies arise with immobilized factor H, which may be artefactual or may reflect the physiological situation. (c) Similarly, binding sites on factor I for C3(NH3) and for factor H do not overlap, and binding of factor H and C3(NH3) to factor I promotes direct factor H-C3(NH3) interactions. Based on these results, a model of the interactions between factor H, factor I and C3(NH3) leading to the processing of C3(NH3) is proposed. | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9291131 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9291131 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9291131 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:9291131 | pubmed:issn | 0264-6021 | lld:pubmed |
| pubmed-article:9291131 | pubmed:author | pubmed-author:SimR BRB | lld:pubmed |
| pubmed-article:9291131 | pubmed:author | pubmed-author:SoamesC JCJ | lld:pubmed |
| pubmed-article:9291131 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9291131 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:9291131 | pubmed:volume | 326 ( Pt 2) | lld:pubmed |
| pubmed-article:9291131 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9291131 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9291131 | pubmed:pagination | 553-61 | lld:pubmed |
| pubmed-article:9291131 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:meshHeading | pubmed-meshheading:9291131-... | lld:pubmed |
| pubmed-article:9291131 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9291131 | pubmed:articleTitle | Interactions between human complement components factor H, factor I and C3b. | lld:pubmed |
| pubmed-article:9291131 | pubmed:affiliation | MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, U.K. | lld:pubmed |
| pubmed-article:9291131 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:718 | entrezgene:pubmed | pubmed-article:9291131 | lld:entrezgene |
| entrez-gene:3075 | entrezgene:pubmed | pubmed-article:9291131 | lld:entrezgene |
| entrez-gene:3426 | entrezgene:pubmed | pubmed-article:9291131 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:9291131 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:9291131 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9291131 | lld:pubmed |
