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pubmed-article:9262248pubmed:abstractTextIt has been known for more than 20 years that estrogen replacement therapy substantially increases a woman's risk of developing endometrial cancer. To reduce this increased risk, progestins have been added to estrogen replacement therapy for between 5 and 15 days (usually 7 or 10 days) per "month" in a sequential fashion (sequential estrogen-progestin replacement therapy) or with each dose of estrogen replacement therapy (continuous combined replacement therapy). At the present time, however, little is known about the effects of varying the number of days that progestin is used in sequential estrogen-progestin replacement therapy.lld:pubmed
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pubmed-article:9262248pubmed:articleTitleEstrogen-progestin replacement therapy and endometrial cancer.lld:pubmed
pubmed-article:9262248pubmed:affiliationDepartment of Preventive Medicine, USC/Norris Comprehensive Cancer Center, Los Angeles, CA 90033-0800, USA.lld:pubmed
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