pubmed-article:9258248 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C0026769 | lld:lifeskim |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C0014063 | lld:lifeskim |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C1136159 | lld:lifeskim |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
pubmed-article:9258248 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
pubmed-article:9258248 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:9258248 | pubmed:dateCreated | 1997-8-26 | lld:pubmed |
pubmed-article:9258248 | pubmed:abstractText | The MHC region on 6p harbors at least one susceptibility gene for multiple sclerosis (MS). Within this region, HLA-DM loci are of interest being involved in class II antigen processing. We investigated the association of HLA-DM polymorphisms with MS. Sixty-three patients with MS and 46 healthy controls from continental Italy were typed for HLA-DM polymorphisms and HLA-DRB1 alleles. Besides, among the donors characterized for the DM polymorphisms, we considered 6 MS patients previously studied for the fine specificity of their MBP-specific T lymphocyte lines (TLL). The frequencies of allelic variants at the DMA and DMB loci were similar between MS patients and controls, even when HLA-DRB1*1501 positive and negative donors were analyzed separately. Patients with predominant responses to different MBP epitopes did not differ for their HLA-DM haplotype while patients with predominant responses to the same MBP epitope could present different HLA-DM haplotypes. HLA-DM polymorphisms do not associate with MS and may not affect specific patterns of T cell responses to MBP. | lld:pubmed |
pubmed-article:9258248 | pubmed:language | eng | lld:pubmed |
pubmed-article:9258248 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9258248 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9258248 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9258248 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9258248 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9258248 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9258248 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9258248 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9258248 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9258248 | pubmed:month | Aug | lld:pubmed |
pubmed-article:9258248 | pubmed:issn | 0165-5728 | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:ContuLL | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:LalPP | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:FlorioPP | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:RistoriGG | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:Di GiovanniSS | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:SalvettiMM | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:PozzilliCC | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:ButtinelliCC | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:CarcassiCC | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:FioriPP | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:CaccianiAA | lld:pubmed |
pubmed-article:9258248 | pubmed:author | pubmed-author:Montesperelli... | lld:pubmed |
pubmed-article:9258248 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9258248 | pubmed:volume | 77 | lld:pubmed |
pubmed-article:9258248 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9258248 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9258248 | pubmed:pagination | 181-4 | lld:pubmed |
pubmed-article:9258248 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
pubmed-article:9258248 | pubmed:meshHeading | pubmed-meshheading:9258248-... | lld:pubmed |
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pubmed-article:9258248 | pubmed:year | 1997 | lld:pubmed |
pubmed-article:9258248 | pubmed:articleTitle | HLA-DM polymorphisms do not associate with multiple sclerosis: an association study with analysis of myelin basic protein T cell specificity. | lld:pubmed |
pubmed-article:9258248 | pubmed:affiliation | Dipartimento di Scienze Neurologiche, Università La Sapienza, Roma, Italy. | lld:pubmed |
pubmed-article:9258248 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9258248 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9258248 | lld:pubmed |