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pubmed-article:9253618pubmed:abstractTextRecombinant alpha-interferon (r-IFN) is an effective therapy for chronic myeloid leukaemia (CML), inducing haematological and major cytogenetic response in 70% and 30% of patients, respectively. In this study we have evaluated the significance of bone marrow (BM) histology on the subsequent response to r-IFN therapy, as well as the morphological changes induced by r-IFN within BM.lld:pubmed
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pubmed-article:9253618pubmed:articleTitleHistopathological changes in bone marrow biopsies from patients with chronic myeloid leukaemia after treatment with recombinant alpha-interferon.lld:pubmed
pubmed-article:9253618pubmed:affiliationDepartment of Pathology, Spedali Civili, University of Brescia, Italy.lld:pubmed
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