| pubmed-article:9239306 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9239306 | lifeskim:mentions | umls-concept:C0521009 | lld:lifeskim |
| pubmed-article:9239306 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:9239306 | lifeskim:mentions | umls-concept:C0302908 | lld:lifeskim |
| pubmed-article:9239306 | lifeskim:mentions | umls-concept:C0017127 | lld:lifeskim |
| pubmed-article:9239306 | lifeskim:mentions | umls-concept:C0023810 | lld:lifeskim |
| pubmed-article:9239306 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:9239306 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9239306 | pubmed:dateCreated | 1997-11-13 | lld:pubmed |
| pubmed-article:9239306 | pubmed:abstractText | The objectives of the present investigation were 1) to study the effect of bacterial lipopolysaccharide (LPS) on rat gastric emptying (GE) and 2) to investigate a possible involvement of the vagus nerve in the gastric action of LPS. Endotoxin from E. coli (strain 055:B5) was administered sc, ip or iv to male Wistar rats (220-280 g body weight) at a maximum dose of 50 micrograms/kg animal weight. Control animals received an equivalent volume of sterile saline solution. At a given time period after LPS administration, GE was evaluated by measuring gastric retention 10 min after the orogastric infusion of a test meal (2 ml/100 g animal weight), which consisted of 0.9% NaCl plus the marker phenol red (6 mg/dl). One group of animals was subjected to bilateral subdiaphragmatic vagotomy or sham operation 15 days before the test. A significant delay in GE of the test meal was observed 5 h after iv administration of the endotoxin at the dose of 50 micrograms/kg animal weight. The LPS-induced delay of GE was detected as early as 30 min and up to 8 h after endotoxin administration. The use of different doses of LPS ranging from 5 to 50 micrograms/kg animal weight showed that the alteration of GE was dose dependent. In addition, vagotomized animals receiving LPS displayed a GE that was not significantly different from that of the sham control group. However, a participation of the vagus nerve in LPS-induced delay in GE could not be clearly demonstrated by these experiments since vagotomy itself induced changes in this gastric parameter. The present study provides a suitable model for identifying the mechanisms underlying the effects of LPS on gastric emptying. | lld:pubmed |
| pubmed-article:9239306 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9239306 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9239306 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9239306 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9239306 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9239306 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:9239306 | pubmed:issn | 0100-879X | lld:pubmed |
| pubmed-article:9239306 | pubmed:author | pubmed-author:CollaresE FEF | lld:pubmed |
| pubmed-article:9239306 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9239306 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:9239306 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9239306 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9239306 | pubmed:pagination | 207-11 | lld:pubmed |
| pubmed-article:9239306 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:meshHeading | pubmed-meshheading:9239306-... | lld:pubmed |
| pubmed-article:9239306 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9239306 | pubmed:articleTitle | Effect of bacterial lipopolysaccharide on gastric emptying of liquids in rats. | lld:pubmed |
| pubmed-article:9239306 | pubmed:affiliation | Departamento de Pediatria and Núcleo de Medicina e Cirurgia Experimental, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, SP, Brasil. | lld:pubmed |
| pubmed-article:9239306 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9239306 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9239306 | lld:pubmed |
