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pubmed-article:9224703 | lifeskim:mentions | umls-concept:C1704787 | lld:lifeskim |
pubmed-article:9224703 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:9224703 | pubmed:dateCreated | 1997-8-1 | lld:pubmed |
pubmed-article:9224703 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9224703 | pubmed:abstractText | FMRFamide-related peptides have been isolated from both invertebrates and vertebrates and exhibit a wide range of biological effects in rats. We show here that in humans 2 FMRFamide-related peptides are encoded by a single gene expressed as a spliced mRNA. The larger predicted peptide (AGEGLNSQFWSLAAPQRFamide) differs from the peptide isolated from bovines (AGEGLSSPFWSLAAPQRFamide) by the substitutions of 2 amino acids. The shorter predicted peptide (NPSF, SQAFLFQPQRFamide) is 3 amino acids longer than the bovine 8 amino-acid NPFF (FLFQPQRFamide) or the human NPFF peptide isolated from serum [5], suggesting that the encoded protein is subject to cleavage by a tripeptidyl peptidase or by a novel processing mechanism. On rat spinal cord, the larger peptide is indistinguishable in activity from the equivalent bovine peptide whereas the smaller extended peptide is inactive. | lld:pubmed |
pubmed-article:9224703 | pubmed:language | eng | lld:pubmed |
pubmed-article:9224703 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9224703 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:9224703 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9224703 | pubmed:month | Jun | lld:pubmed |
pubmed-article:9224703 | pubmed:issn | 0014-5793 | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:WalkerR JRJ | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:WilsonSS | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:SharmaRR | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:BurkeJ FJF | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:BagustJJ | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:PerryS JSJ | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:CroneNN | lld:pubmed |
pubmed-article:9224703 | pubmed:author | pubmed-author:Yi-Kung... | lld:pubmed |
pubmed-article:9224703 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9224703 | pubmed:day | 16 | lld:pubmed |
pubmed-article:9224703 | pubmed:volume | 409 | lld:pubmed |
pubmed-article:9224703 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9224703 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9224703 | pubmed:pagination | 426-30 | lld:pubmed |
pubmed-article:9224703 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:9224703 | pubmed:year | 1997 | lld:pubmed |
pubmed-article:9224703 | pubmed:articleTitle | A human gene encoding morphine modulating peptides related to NPFF and FMRFamide. | lld:pubmed |
pubmed-article:9224703 | pubmed:affiliation | Sussex Centre for Neuroscience, University of Sussex, Brighton, UK. | lld:pubmed |
pubmed-article:9224703 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9224703 | pubmed:publicationType | Comparative Study | lld:pubmed |
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