| pubmed-article:9181965 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9181965 | lifeskim:mentions | umls-concept:C0007603 | lld:lifeskim |
| pubmed-article:9181965 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:9181965 | lifeskim:mentions | umls-concept:C0007605 | lld:lifeskim |
| pubmed-article:9181965 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:9181965 | lifeskim:mentions | umls-concept:C2610925 | lld:lifeskim |
| pubmed-article:9181965 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9181965 | pubmed:dateCreated | 1997-6-12 | lld:pubmed |
| pubmed-article:9181965 | pubmed:abstractText | Parameters of the Ca2+ permeability (the 45Ca influx rate in the presence of orthovanadate blocking the Ca(2+)-ATPhase, and the initial rate of the 45Ca uptake) and the DNA fragmentation were determined in rat thymocytes after gamma-irradiation-induced (with a dose of 5 Gy) apoptosis. Within the first 30-90 min after irradiation, the 45Ca influx rate that is characteristic of the membrane passive permeability remained unchanged. The initial rate of the 45Ca uptake that is characteristic of the Ca2+ exchange almost doubled. In 90-180 min, the rate of the 45Ca influx in the irradiated cells increased 1.5 to 2.0 times. An increase in the DNA fragmentation was observed in 90-120 min after irradiation of thymocytes; in 3 h, it developed up to 50%. Thus, modification of the membrane Ca2+ permeability in the irradiated thymocytes precedes a stage of initiation of the DNA degradation. A degree of disturbance of the membrane passive permeability increases as the thymocyte apoptosis progresses. The obtained data suggest that disturbance of the passive Ca2+ permeability and the intracellular Ca2+ homeostasis are responsible for the apoptosis of lethally irradiated thymocytes. | lld:pubmed |
| pubmed-article:9181965 | pubmed:language | rus | lld:pubmed |
| pubmed-article:9181965 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9181965 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9181965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9181965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9181965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9181965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9181965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9181965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9181965 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9181965 | pubmed:issn | 0869-8031 | lld:pubmed |
| pubmed-article:9181965 | pubmed:author | pubmed-author:ShevchenkoA... | lld:pubmed |
| pubmed-article:9181965 | pubmed:author | pubmed-author:Gaba?V LVL | lld:pubmed |
| pubmed-article:9181965 | pubmed:author | pubmed-author:ShevchenkoT... | lld:pubmed |
| pubmed-article:9181965 | pubmed:author | pubmed-author:KobialkoV OVO | lld:pubmed |
| pubmed-article:9181965 | pubmed:author | pubmed-author:MakarovaIu... | lld:pubmed |
| pubmed-article:9181965 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9181965 | pubmed:volume | 37 | lld:pubmed |
| pubmed-article:9181965 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9181965 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9181965 | pubmed:pagination | 220-7 | lld:pubmed |
| pubmed-article:9181965 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9181965 | pubmed:meshHeading | pubmed-meshheading:9181965-... | lld:pubmed |
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| pubmed-article:9181965 | pubmed:articleTitle | [Increased plasma membrane permeability for Ca2+ in radiation-induced thymocyte apoptosis]. | lld:pubmed |
| pubmed-article:9181965 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9181965 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:9181965 | pubmed:publicationType | English Abstract | lld:pubmed |
