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pubmed-article:9164228pubmed:abstractTextDolasetron is a 5-HT3 antagonist antiemetic with active oral and intravenous formulations. The effects of this class are enhanced when combined with dexamethasone. This study tested the ability of the combination of oral dolasetron 200 mg and oral dexamethasone 20 mg to prevent acute emesis in cancer patients receiving initial cisplatin at doses > or = 70 mg/m2. Additionally, patients were randomly assigned to receive a second dosage of the regimen 16 hours later to improve control of acute symptoms.lld:pubmed
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pubmed-article:9164228pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:9164228pubmed:articleTitlePrevention of acute emesis in cancer patients following high-dose cisplatin with the combination of oral dolasetron and dexamethasone.lld:pubmed
pubmed-article:9164228pubmed:affiliationDepartment of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. krism@mskcc.orglld:pubmed
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