| pubmed-article:9158012 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9158012 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
| pubmed-article:9158012 | lifeskim:mentions | umls-concept:C0042396 | lld:lifeskim |
| pubmed-article:9158012 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:9158012 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:9158012 | pubmed:dateCreated | 1997-6-6 | lld:pubmed |
| pubmed-article:9158012 | pubmed:abstractText | Cyclosporine (CsA)-induced nephrotoxicity may be due to intrarenal vasoconstriction and glomerular hypoperfusion. Several factors, including endothelin and prostanoids, are suggested mediators of this response. Recent evidence suggests that CsA leads to increased oxygen-derived free radical (ODFR) production and lipid peroxidation in renal tissue. Whether this leads to alterations in renal vessel reactivity is unclear. Lazaroids, such as U74389G, are radical-quenching antioxidants that inhibit ODFR-induced lipid peroxidation and may improve renal function after ischemia and reperfusion. We hypothesized that ODFRs contribute to CsA-induced alterations of the renal microcirculation. | lld:pubmed |
| pubmed-article:9158012 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9158012 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9158012 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9158012 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9158012 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9158012 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9158012 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9158012 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9158012 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9158012 | pubmed:month | May | lld:pubmed |
| pubmed-article:9158012 | pubmed:issn | 0041-1337 | lld:pubmed |
| pubmed-article:9158012 | pubmed:author | pubmed-author:GarrisonR NRN | lld:pubmed |
| pubmed-article:9158012 | pubmed:author | pubmed-author:WilsonM AMA | lld:pubmed |
| pubmed-article:9158012 | pubmed:author | pubmed-author:BentleyF RFR | lld:pubmed |
| pubmed-article:9158012 | pubmed:author | pubmed-author:SpainD ADA | lld:pubmed |
| pubmed-article:9158012 | pubmed:author | pubmed-author:KrysztopikR... | lld:pubmed |
| pubmed-article:9158012 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9158012 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:9158012 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:9158012 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9158012 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9158012 | pubmed:pagination | 1215-20 | lld:pubmed |
| pubmed-article:9158012 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:meshHeading | pubmed-meshheading:9158012-... | lld:pubmed |
| pubmed-article:9158012 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9158012 | pubmed:articleTitle | Lazaroids prevent acute cyclosporine-induced renal vasoconstriction. | lld:pubmed |
| pubmed-article:9158012 | pubmed:affiliation | Department of Surgery, University of Louisville School of Medicine, Kentucky 40292, USA. | lld:pubmed |
| pubmed-article:9158012 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9158012 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:9158012 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
