| pubmed-article:9151260 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9151260 | lifeskim:mentions | umls-concept:C1880371 | lld:lifeskim |
| pubmed-article:9151260 | lifeskim:mentions | umls-concept:C0540621 | lld:lifeskim |
| pubmed-article:9151260 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:9151260 | pubmed:dateCreated | 1997-7-24 | lld:pubmed |
| pubmed-article:9151260 | pubmed:abstractText | Alternating poly(Glu-Leu) was synthesized by the condensation of the corresponding dipeptide p-nitrophenyl ester at high concentration. It exhibits a random coil structure in pure water at neutral pH. Addition of monovalent cations, such as NH4+ to a final 0.1 M solution, induces a transition to a water soluble beta-structure. The salt effect is quite selective since no transition was observed with Li+, Na+ or Cs+ ions. Addition of 0.5 equiv of calcium, cobalt or manganese chlorides per glutamyl residue induces similar coil to beta-sheet transitions. No polymer precipitation was observed at these very low salt concentrations. Addition of 0.5 equiv. of Cu2+ or 0.15 equiv. of Fe3- induces a coil to alpha-helix transition. Molecular modeling has been used to understand tentatively the main factors controlling the different conformations observed with the various metal ions. | lld:pubmed |
| pubmed-article:9151260 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9151260 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9151260 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9151260 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:9151260 | pubmed:issn | 1397-002X | lld:pubmed |
| pubmed-article:9151260 | pubmed:author | pubmed-author:BertrandMM | lld:pubmed |
| pubmed-article:9151260 | pubmed:author | pubmed-author:BrabyPP | lld:pubmed |
| pubmed-article:9151260 | pubmed:author | pubmed-author:TUCC | lld:pubmed |
| pubmed-article:9151260 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9151260 | pubmed:volume | 49 | lld:pubmed |
| pubmed-article:9151260 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9151260 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9151260 | pubmed:pagination | 269-72 | lld:pubmed |
| pubmed-article:9151260 | pubmed:dateRevised | 2000-12-18 | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:meshHeading | pubmed-meshheading:9151260-... | lld:pubmed |
| pubmed-article:9151260 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9151260 | pubmed:articleTitle | Salt-dependent conformational diversity of alternating poly (Glu-Leu). | lld:pubmed |
| pubmed-article:9151260 | pubmed:affiliation | Molecular Biophysics Centre, CNRS, Orléans, France. | lld:pubmed |
| pubmed-article:9151260 | pubmed:publicationType | Journal Article | lld:pubmed |
