| pubmed-article:9128246 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9128246 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:9128246 | lifeskim:mentions | umls-concept:C0887838 | lld:lifeskim |
| pubmed-article:9128246 | lifeskim:mentions | umls-concept:C0887885 | lld:lifeskim |
| pubmed-article:9128246 | lifeskim:mentions | umls-concept:C0024742 | lld:lifeskim |
| pubmed-article:9128246 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:9128246 | lifeskim:mentions | umls-concept:C1522492 | lld:lifeskim |
| pubmed-article:9128246 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9128246 | pubmed:dateCreated | 1997-5-14 | lld:pubmed |
| pubmed-article:9128246 | pubmed:abstractText | The transport of the two mannose 6-phosphate receptors (MPRs) from the secretory pathway to the endocytic pathway is mediated by carrier vesicles coated with the AP-1 Golgi-specific assembly protein and clathrin. Using an in vitro assay that reconstitutes the ARF-1-dependent translocation of cytosolic AP-1 onto membranes of the TGN, we have previously reported that the MPRs are key components for the efficient recruitment of AP-1 (Le Borgne, R., G. Griffiths, and B. Hoflack. 1996. J. Biol. Chem. 271:2162-2170). Using a polyclonal antibody against the mouse gamma-adaptin, we have now examined the steady state distribution of AP-1 after subcellular fractionation of mouse fibroblasts lacking both MPRs or reexpressing physiological levels of either MPR. We report that the amount of AP-1 bound to membranes and associated with clathrin-coated vesicles depends on the expression level of the MPRs and on the integrity of their cytoplasmic domains. Thus, these results indicate that the concentration of the MPRs, i.e., the major transmembrane proteins sorted toward the endosomes, determines the number of clathrin-coated vesicles formed in the TGN. | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9128246 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9128246 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9128246 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:9128246 | pubmed:issn | 0021-9525 | lld:pubmed |
| pubmed-article:9128246 | pubmed:author | pubmed-author:HoflackBB | lld:pubmed |
| pubmed-article:9128246 | pubmed:author | pubmed-author:Le BorgneRR | lld:pubmed |
| pubmed-article:9128246 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9128246 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:9128246 | pubmed:volume | 137 | lld:pubmed |
| pubmed-article:9128246 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9128246 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9128246 | pubmed:pagination | 335-45 | lld:pubmed |
| pubmed-article:9128246 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
| pubmed-article:9128246 | pubmed:meshHeading | pubmed-meshheading:9128246-... | lld:pubmed |
