pubmed-article:9125661 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C0031001 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C0022378 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C0000854 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C0032483 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C1979963 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C2003903 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C2346689 | lld:lifeskim |
pubmed-article:9125661 | lifeskim:mentions | umls-concept:C1550025 | lld:lifeskim |
pubmed-article:9125661 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:9125661 | pubmed:dateCreated | 1997-5-14 | lld:pubmed |
pubmed-article:9125661 | pubmed:abstractText | The study aimed at applying closed segmental intestinal perfusion with a multichannel tube (Loc-I-Gut) for studies of regional small bowel permeability to different-sized polyethylene glycols and to compare jejunal absorption with absorption after oral load in healthy subjects. Intestinal perfusion was performed in 10 healthy volunteers and recovery of (14)C-labeled polyethylene glycol 4000 was used to detect leakage. Absorption of polyethylene glycols 546-942 was measured as urinary recovery after perfusion and oral load, and as disappearance from the lumen during steady-state perfusion. Steady-state conditions were obtained during the second hour of perfusion. Absorption of polyethylene glycols during perfusion was size-selective for molecular weights 546-766, but not for 810-942. After oral load, absorption was size-selective throughout 546-942. Segmental perfusion with Loc-I-Gut may be used to study regional jejunal permeability. Our data support the hypothesis of a dual pore system for absorption of hydrophilic molecules in the human jejunum. | lld:pubmed |
pubmed-article:9125661 | pubmed:language | eng | lld:pubmed |
pubmed-article:9125661 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9125661 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:9125661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9125661 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9125661 | pubmed:month | Apr | lld:pubmed |
pubmed-article:9125661 | pubmed:issn | 0163-2116 | lld:pubmed |
pubmed-article:9125661 | pubmed:author | pubmed-author:TagessonCC | lld:pubmed |
pubmed-article:9125661 | pubmed:author | pubmed-author:SjödahlRR | lld:pubmed |
pubmed-article:9125661 | pubmed:author | pubmed-author:KalbCC | lld:pubmed |
pubmed-article:9125661 | pubmed:author | pubmed-author:OlaisonGG | lld:pubmed |
pubmed-article:9125661 | pubmed:author | pubmed-author:SöderholmJ... | lld:pubmed |
pubmed-article:9125661 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9125661 | pubmed:volume | 42 | lld:pubmed |
pubmed-article:9125661 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9125661 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9125661 | pubmed:pagination | 853-7 | lld:pubmed |
pubmed-article:9125661 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:9125661 | pubmed:meshHeading | pubmed-meshheading:9125661-... | lld:pubmed |
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pubmed-article:9125661 | pubmed:meshHeading | pubmed-meshheading:9125661-... | lld:pubmed |
pubmed-article:9125661 | pubmed:year | 1997 | lld:pubmed |
pubmed-article:9125661 | pubmed:articleTitle | Absorption profiles for polyethylene glycols after regional jejunal perfusion and oral load in healthy humans. | lld:pubmed |
pubmed-article:9125661 | pubmed:affiliation | Department of Surgery, University Hospital, Linköping, Sweden. | lld:pubmed |
pubmed-article:9125661 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9125661 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:9125661 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |