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pubmed-article:898897pubmed:abstractTextExperiments revealed parallelism between the duration of the main manifestations of the hyporeactivity phenomenon (tolerance) in interferon induction and the duration of detection of a masked infection with the inducer virus (Newcastle disease virus) in peritoneal exudate cells of tolerant mice. It was also shown that after contact of chick fibroblasts with a dose of interferon which completely inhibited replication of vesicular stomatitis virus infecting the cells this virus was found in the cells in the masked form. Persistence of a virus interferon inducer in the masked form appears to play a significant role in the mechanism of tolerance as well as creation in the interferon-treated cells of conditions for masking viruses infecting these cells.lld:pubmed
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pubmed-article:898897pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:898897pubmed:articleTitle[Relationship between manifestation of hyporeactivity (tolerance) in interferon production and the presence of a viral interferon inductor in the cells of the tolerant animal].lld:pubmed
pubmed-article:898897pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:898897pubmed:publicationTypeEnglish Abstractlld:pubmed