| pubmed-article:8981397 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8981397 | lifeskim:mentions | umls-concept:C0041412 | lld:lifeskim |
| pubmed-article:8981397 | lifeskim:mentions | umls-concept:C0327106 | lld:lifeskim |
| pubmed-article:8981397 | lifeskim:mentions | umls-concept:C1565000 | lld:lifeskim |
| pubmed-article:8981397 | lifeskim:mentions | umls-concept:C0022471 | lld:lifeskim |
| pubmed-article:8981397 | lifeskim:mentions | umls-concept:C0037492 | lld:lifeskim |
| pubmed-article:8981397 | lifeskim:mentions | umls-concept:C1533157 | lld:lifeskim |
| pubmed-article:8981397 | pubmed:issue | 15-17 | lld:pubmed |
| pubmed-article:8981397 | pubmed:dateCreated | 1997-4-1 | lld:pubmed |
| pubmed-article:8981397 | pubmed:abstractText | The aim of this study was to investigate the effects of excitatory amino acids on channels found in horizontal cell membranes using patch-clamp techniques. We unexpectedly found that the excitatory amino acid receptor agonist, kainic acid, reversibly inhibited the transient tetrodotoxin (TTX)-sensitive Na+ current in isolated horizontal cell bodies and axons from the retina of the turtle (Pseudemys scripta elegans). The effect of kainic acid was antagonized by the glutamate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione. Kainic acid activated a non-selective cation current, a finding that was consistent with previous reports, and which would account for the kainate induced depolarisation of these cells. The inhibition of the transient TTX-sensitive Na+ current by kainic acid might be important in the modification of the kinetics of responses to excitatory amino acid analogues often observed during intracellular recording from these cells. | lld:pubmed |
| pubmed-article:8981397 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8981397 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8981397 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8981397 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8981397 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8981397 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8981397 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8981397 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:8981397 | pubmed:issn | 0959-4965 | lld:pubmed |
| pubmed-article:8981397 | pubmed:author | pubmed-author:MartinD KDK | lld:pubmed |
| pubmed-article:8981397 | pubmed:author | pubmed-author:MillarT JTJ | lld:pubmed |
| pubmed-article:8981397 | pubmed:author | pubmed-author:AndertonP JPJ | lld:pubmed |
| pubmed-article:8981397 | pubmed:author | pubmed-author:Le DainA CAC | lld:pubmed |
| pubmed-article:8981397 | pubmed:author | pubmed-author:BursillJ AJA | lld:pubmed |
| pubmed-article:8981397 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8981397 | pubmed:day | 4 | lld:pubmed |
| pubmed-article:8981397 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:8981397 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8981397 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8981397 | pubmed:pagination | 2429-33 | lld:pubmed |
| pubmed-article:8981397 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8981397 | pubmed:meshHeading | pubmed-meshheading:8981397-... | lld:pubmed |
| pubmed-article:8981397 | pubmed:meshHeading | pubmed-meshheading:8981397-... | lld:pubmed |
| pubmed-article:8981397 | pubmed:meshHeading | pubmed-meshheading:8981397-... | lld:pubmed |
| pubmed-article:8981397 | pubmed:meshHeading | pubmed-meshheading:8981397-... | lld:pubmed |
| pubmed-article:8981397 | pubmed:meshHeading | pubmed-meshheading:8981397-... | lld:pubmed |
| pubmed-article:8981397 | pubmed:meshHeading | pubmed-meshheading:8981397-... | lld:pubmed |
| pubmed-article:8981397 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8981397 | pubmed:articleTitle | Kainic acid blocks a TTX-sensitive sodium channel in retinal horizontal cells of the turtle (Pseudemys scripta elegans). | lld:pubmed |
| pubmed-article:8981397 | pubmed:affiliation | Department of Clinical Pharmacology, St. Vincent's Hospital, Darlinghurst, NSW, Australia. | lld:pubmed |
| pubmed-article:8981397 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8981397 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
