pubmed-article:896463 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:896463 | lifeskim:mentions | umls-concept:C0015008 | lld:lifeskim |
pubmed-article:896463 | lifeskim:mentions | umls-concept:C0184511 | lld:lifeskim |
pubmed-article:896463 | lifeskim:mentions | umls-concept:C0184661 | lld:lifeskim |
pubmed-article:896463 | lifeskim:mentions | umls-concept:C0178587 | lld:lifeskim |
pubmed-article:896463 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
pubmed-article:896463 | lifeskim:mentions | umls-concept:C2699488 | lld:lifeskim |
pubmed-article:896463 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:896463 | pubmed:dateCreated | 1977-10-28 | lld:pubmed |
pubmed-article:896463 | pubmed:abstractText | Analogues of ethidium chloride with large quaternary side chains have been synthesized and evaluated for improved resolution in the dye-buoyant density system for the separation of open and closed circular DNA. These compounds are similar to propidium which differs from ethidium by the replacement of an ethyl group by a methyldiethylaminopropyl group. The new analogues contain a triethylamino group attached to a methylene chain with 3, 5 or 7 carbons. With PM2 DNA the observed separation for propidium is 1.97 times that of ethidium and the new dyes show separations relative to ethidium of 2.27, 2.66 and 2.77. A correlation is established between the mass of the dye component and the observed separation which is retionalized on the basis of the four component thermodynamics describing this system. | lld:pubmed |
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pubmed-article:896463 | pubmed:language | eng | lld:pubmed |
pubmed-article:896463 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:896463 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:896463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:896463 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:896463 | pubmed:issn | 0305-1048 | lld:pubmed |
pubmed-article:896463 | pubmed:author | pubmed-author:HudsonBB | lld:pubmed |
pubmed-article:896463 | pubmed:author | pubmed-author:DawsonJ HJH | lld:pubmed |
pubmed-article:896463 | pubmed:author | pubmed-author:MosherC WCW | lld:pubmed |
pubmed-article:896463 | pubmed:author | pubmed-author:DesiderioRR | lld:pubmed |
pubmed-article:896463 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:896463 | pubmed:volume | 4 | lld:pubmed |
pubmed-article:896463 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:896463 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:896463 | pubmed:pagination | 1349-59 | lld:pubmed |
pubmed-article:896463 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:896463 | pubmed:meshHeading | pubmed-meshheading:896463-E... | lld:pubmed |
pubmed-article:896463 | pubmed:year | 1977 | lld:pubmed |
pubmed-article:896463 | pubmed:articleTitle | Ethidium analogues with improved resolution in the dye-buoyant density procedure. | lld:pubmed |
pubmed-article:896463 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:896463 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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