Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:8910628rdf:typepubmed:Citationlld:pubmed
pubmed-article:8910628lifeskim:mentionsumls-concept:C0375071lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C0033325lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C2350570lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C0677055lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C0078058lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C0017262lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C1171892lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C0178587lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C2911684lld:lifeskim
pubmed-article:8910628lifeskim:mentionsumls-concept:C0185117lld:lifeskim
pubmed-article:8910628pubmed:issue2lld:pubmed
pubmed-article:8910628pubmed:dateCreated1997-1-2lld:pubmed
pubmed-article:8910628pubmed:abstractTextMicrovessel density (MVD) and expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF), acting as a highly specific inducer of angiogenesis, were evaluated in tissue specimens of 25 patients with squamous cell cancer of the vulva. MVD was quantified by immunostaining for factor VIII-related antigen at one field of 0.25 mm2. VPF/VEGF expression was evaluated immunohistochemically using a monoclonal anti-VEGF antibody. FIGO stages I, II, and III were diagnosed in 12, 7, and 6 patients, respectively. MVD >20/field was found in 10 of 25 tumors and moderate or strong expression of VPF/VEGF in 10 of 25 tumors. High MVD was significantly more frequent in tumors with moderate or strong VPF/VEGF expression compared to tumors with no or weak VPF/VEGF expression (P = 0.01). Overall survival rates of patients with tumors of high MVD (P = 0.01) and strong VPF/VEGF expression (P < 0.01) were significantly poorer compared to those patients with low MVD or poor VPF/VEGF expression. Strong VPF/VEGF expression and high MVD are considered important parameters of tumor angiogenesis and therefore are related to poor survival probability in vulvar cancer patients.lld:pubmed
pubmed-article:8910628pubmed:languageenglld:pubmed
pubmed-article:8910628pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8910628pubmed:citationSubsetIMlld:pubmed
pubmed-article:8910628pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8910628pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8910628pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8910628pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8910628pubmed:statusMEDLINElld:pubmed
pubmed-article:8910628pubmed:monthNovlld:pubmed
pubmed-article:8910628pubmed:issn0090-8258lld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:LeodolterSSlld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:BreiteneckerG...lld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:GitschGGlld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:KainzCClld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:KohlbergerPPlld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:ObermairAAlld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:ReinthallerAAlld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:SliutzGGlld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:TempferCClld:pubmed
pubmed-article:8910628pubmed:authorpubmed-author:Bancher-Todes...lld:pubmed
pubmed-article:8910628pubmed:issnTypePrintlld:pubmed
pubmed-article:8910628pubmed:volume63lld:pubmed
pubmed-article:8910628pubmed:ownerNLMlld:pubmed
pubmed-article:8910628pubmed:authorsCompleteYlld:pubmed
pubmed-article:8910628pubmed:pagination204-9lld:pubmed
pubmed-article:8910628pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:meshHeadingpubmed-meshheading:8910628-...lld:pubmed
pubmed-article:8910628pubmed:year1996lld:pubmed
pubmed-article:8910628pubmed:articleTitleInfluence of microvessel density and vascular permeability factor/vascular endothelial growth factor expression on prognosis in vulvar cancer.lld:pubmed
pubmed-article:8910628pubmed:affiliationDepartment of Gynecology and Obstetrics, University Hospital of Vienna, Austria.lld:pubmed
pubmed-article:8910628pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8910628pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8910628lld:pubmed