pubmed-article:8910628 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C0375071 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C0033325 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C2350570 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C0677055 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C0078058 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C1171892 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C0178587 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:8910628 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:8910628 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:8910628 | pubmed:dateCreated | 1997-1-2 | lld:pubmed |
pubmed-article:8910628 | pubmed:abstractText | Microvessel density (MVD) and expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF), acting as a highly specific inducer of angiogenesis, were evaluated in tissue specimens of 25 patients with squamous cell cancer of the vulva. MVD was quantified by immunostaining for factor VIII-related antigen at one field of 0.25 mm2. VPF/VEGF expression was evaluated immunohistochemically using a monoclonal anti-VEGF antibody. FIGO stages I, II, and III were diagnosed in 12, 7, and 6 patients, respectively. MVD >20/field was found in 10 of 25 tumors and moderate or strong expression of VPF/VEGF in 10 of 25 tumors. High MVD was significantly more frequent in tumors with moderate or strong VPF/VEGF expression compared to tumors with no or weak VPF/VEGF expression (P = 0.01). Overall survival rates of patients with tumors of high MVD (P = 0.01) and strong VPF/VEGF expression (P < 0.01) were significantly poorer compared to those patients with low MVD or poor VPF/VEGF expression. Strong VPF/VEGF expression and high MVD are considered important parameters of tumor angiogenesis and therefore are related to poor survival probability in vulvar cancer patients. | lld:pubmed |
pubmed-article:8910628 | pubmed:language | eng | lld:pubmed |
pubmed-article:8910628 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8910628 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8910628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8910628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8910628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8910628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8910628 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8910628 | pubmed:month | Nov | lld:pubmed |
pubmed-article:8910628 | pubmed:issn | 0090-8258 | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:LeodolterSS | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:BreiteneckerG... | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:GitschGG | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:KainzCC | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:KohlbergerPP | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:ObermairAA | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:ReinthallerAA | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:SliutzGG | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:TempferCC | lld:pubmed |
pubmed-article:8910628 | pubmed:author | pubmed-author:Bancher-Todes... | lld:pubmed |
pubmed-article:8910628 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8910628 | pubmed:volume | 63 | lld:pubmed |
pubmed-article:8910628 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8910628 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8910628 | pubmed:pagination | 204-9 | lld:pubmed |
pubmed-article:8910628 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:8910628 | pubmed:meshHeading | pubmed-meshheading:8910628-... | lld:pubmed |
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pubmed-article:8910628 | pubmed:meshHeading | pubmed-meshheading:8910628-... | lld:pubmed |
pubmed-article:8910628 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8910628 | pubmed:articleTitle | Influence of microvessel density and vascular permeability factor/vascular endothelial growth factor expression on prognosis in vulvar cancer. | lld:pubmed |
pubmed-article:8910628 | pubmed:affiliation | Department of Gynecology and Obstetrics, University Hospital of Vienna, Austria. | lld:pubmed |
pubmed-article:8910628 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8910628 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8910628 | lld:pubmed |