| pubmed-article:8906799 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C0007587 | lld:lifeskim |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C0534100 | lld:lifeskim |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C0333516 | lld:lifeskim |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C1539477 | lld:lifeskim |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:8906799 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:8906799 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:8906799 | pubmed:dateCreated | 1996-12-31 | lld:pubmed |
| pubmed-article:8906799 | pubmed:abstractText | Fas/APO-1 and TNF receptor 1 share a common signaling motif in their cytoplasmic tail called the "death domain." Using the death domain as bait in the yeast two-hybrid system, several death domain-containing proteins that participate in cell death signaling have been identified. Here we report the isolation of a novel protein, sentrin, which interacts with Fas/APO-1 and TNF receptor 1 but not with FADD/MORT1 or CD40. Two-hybrid interaction assays reveal that sentrin associates only with the signal-competent forms of Fas/APO-1 or TNF receptor 1 death domains. Sentrin is a novel protein of 101 amino acids with homology to ubiquitin, Nedd8, and a Saccharomyces cerevisiae protein, Smt3. When overexpressed, sentrin provides protection against both anti-Fas/APO-1 and TNF-induced cell death. | lld:pubmed |
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| pubmed-article:8906799 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:8906799 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8906799 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8906799 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:8906799 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:WadaTT | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:OkuraII | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:KamitaniTT | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:ChangH MHM | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:OkuraTT | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:SENK NKN | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:WeiC FCF | lld:pubmed |
| pubmed-article:8906799 | pubmed:author | pubmed-author:GoodPP | lld:pubmed |
| pubmed-article:8906799 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8906799 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:8906799 | pubmed:volume | 157 | lld:pubmed |
| pubmed-article:8906799 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8906799 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8906799 | pubmed:pagination | 4277-81 | lld:pubmed |
| pubmed-article:8906799 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:8906799 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8906799 | pubmed:articleTitle | Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin. | lld:pubmed |
| pubmed-article:8906799 | pubmed:affiliation | Division of Molecular Medicine, The University of Texas-Houston Health Science Center 77030, USA. | lld:pubmed |
| pubmed-article:8906799 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8906799 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8906799 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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