| pubmed-article:8902529 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C0013343 | lld:lifeskim |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C0682529 | lld:lifeskim |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C0023775 | lld:lifeskim |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C0023089 | lld:lifeskim |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C0162524 | lld:lifeskim |
| pubmed-article:8902529 | lifeskim:mentions | umls-concept:C0383763 | lld:lifeskim |
| pubmed-article:8902529 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:8902529 | pubmed:dateCreated | 1997-2-18 | lld:pubmed |
| pubmed-article:8902529 | pubmed:abstractText | The C-525 laser dye at micromolar concentration range is shown to enhance up to two to three orders of magnitude the chemiluminescence (CL) accompanying tert-butyl hydroperoxide (t-BHP)-induced rat liver microsome oxidation and Fe(2+)-induced lipid peroxidation (LPO) in liposomes. C-525 is shown to be a more efficient sensitizer of CL accompanying LPO in membrane systems than the known low-energy excited triplet carbonyl sensitizer, chlorophyll-alpha, (Cl-a). Regarding the sensitization mechanism, C-525 and Cl-a were compared in (a) a peroxyl radical-producing system (2,2'-azobis(2-dimethylvaleronitrile) (AMVN); (b) excited carbonyl-producing systems (3-hydroxymethyl-3,4,4-trimethyl-1,2-dioxetane (HTMD) thermal decomposition and horseradish peroxidase (HRP)-catalyzed isobutanal oxidation); and (c) excited singlet oxygen-producing system [endoperoxide of 3,3-(1,4-naphthylidene)-dipropionate (NDPO2)]. C-525 sensitized CL only in the systems where peroxyl radical and/or triplet excited carbonyls are produced, the mechanism of CL sensitization apparently is energy transfer from the excited triplet carbonyls formed in the peroxyl radical self-reaction via Russell's mechanism or by dioxetane decomposition. Cl-a was found to considerably sensitize CL related to NDPO2 thermal decomposition, a source of singlet oxygen, in addition to acting as a sensitizer of triplet carbonyl CL. The chemical stability of the C-525 laser dye in excited state-generating systems was shown to be appropriate for its application as a sensitizer of CL related to LPO reactions in membranes, but not in the HRP-catalyzed peroxidation system. | lld:pubmed |
| pubmed-article:8902529 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:8902529 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8902529 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8902529 | pubmed:issn | 0891-5849 | lld:pubmed |
| pubmed-article:8902529 | pubmed:author | pubmed-author:SiewDD | lld:pubmed |
| pubmed-article:8902529 | pubmed:author | pubmed-author:SharovV SVS | lld:pubmed |
| pubmed-article:8902529 | pubmed:author | pubmed-author:BrivibaKK | lld:pubmed |
| pubmed-article:8902529 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8902529 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:8902529 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8902529 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8902529 | pubmed:pagination | 833-43 | lld:pubmed |
| pubmed-article:8902529 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:8902529 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8902529 | pubmed:articleTitle | Assessment of the C-525 laser dye as a chemiluminescence sensitizer for lipid peroxidation in biological membranes: a comparison with chlorophyll-a. | lld:pubmed |
| pubmed-article:8902529 | pubmed:affiliation | Institut für Physiologische Chemie I, Heinrich-Heine-Universität Düsseldorf, Germany. | lld:pubmed |
| pubmed-article:8902529 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8902529 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8902529 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8902529 | lld:pubmed |
