| pubmed-article:8897973 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8897973 | lifeskim:mentions | umls-concept:C0016452 | lld:lifeskim |
| pubmed-article:8897973 | lifeskim:mentions | umls-concept:C0001554 | lld:lifeskim |
| pubmed-article:8897973 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8897973 | lifeskim:mentions | umls-concept:C0013123 | lld:lifeskim |
| pubmed-article:8897973 | lifeskim:mentions | umls-concept:C0205099 | lld:lifeskim |
| pubmed-article:8897973 | lifeskim:mentions | umls-concept:C0061359 | lld:lifeskim |
| pubmed-article:8897973 | pubmed:issue | 4 Pt 2 | lld:pubmed |
| pubmed-article:8897973 | pubmed:dateCreated | 1996-12-16 | lld:pubmed |
| pubmed-article:8897973 | pubmed:abstractText | Glucagon-like peptide (GLP)-1-(7-36) amide and its pancreatic receptors are important for control of blood glucose levels. However, rat GLP-1 receptors are also localized in the brain, in hypothalamus, and in areas without a blood-brain barrier. When rats were kept on a food restriction schedule, intracerebroventricular injection of GLP-1 just before food was offered inhibited food intake. However, peripheral GLP-1 administration by intraperitoneal injection had little effect. GLP-1 effects on water intake and output were also investigated. Intracerebroventricular GLP-1 profoundly inhibited angiotensin II-induced drinking behavior in rats, and water intake was suppressed by exogenous GLP-1 in rats habituated to a water restriction schedule. These effects were reproduced by intraperitoneal administration of GLP-1. Furthermore, intracerebroventricular GLP-1 stimulated urinary excretion of water and sodium. The centrally elicited effects were blocked by the GLP-1 antagonist exendin-(9-39) amide, whereas the N-terminally extended and inactive GLP-1-(1-36) amide had no effect on feeding and drinking. GLP-1 had no effect in behavioral assays measuring exploratory locomotor activity and conditioned taste aversion. In conclusion, GLP-1 may play a physiological role in regulation of both ingestion and the water and salt homeostasis. | lld:pubmed |
| pubmed-article:8897973 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8897973 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8897973 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8897973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8897973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8897973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8897973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8897973 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8897973 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8897973 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8897973 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:8897973 | pubmed:author | pubmed-author:MøllerMM | lld:pubmed |
| pubmed-article:8897973 | pubmed:author | pubmed-author:LarsenP JPJ | lld:pubmed |
| pubmed-article:8897973 | pubmed:author | pubmed-author:JessopD SDS | lld:pubmed |
| pubmed-article:8897973 | pubmed:author | pubmed-author:GökeRR | lld:pubmed |
| pubmed-article:8897973 | pubmed:author | pubmed-author:SheikhS PSP | lld:pubmed |
| pubmed-article:8897973 | pubmed:author | pubmed-author:Fink-JensenAA | lld:pubmed |
| pubmed-article:8897973 | pubmed:author | pubmed-author:Tang-Christen... | lld:pubmed |
| pubmed-article:8897973 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8897973 | pubmed:volume | 271 | lld:pubmed |
| pubmed-article:8897973 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8897973 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8897973 | pubmed:pagination | R848-56 | lld:pubmed |
| pubmed-article:8897973 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:meshHeading | pubmed-meshheading:8897973-... | lld:pubmed |
| pubmed-article:8897973 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8897973 | pubmed:articleTitle | Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. | lld:pubmed |
| pubmed-article:8897973 | pubmed:affiliation | Department of Clinical Biochemistry 7642, State University Hospital of Copenhagen, Denmark. | lld:pubmed |
| pubmed-article:8897973 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8897973 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8897973 | lld:pubmed |
