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pubmed-article:8860424pubmed:abstractTextDNA plasmids (pDNA) can be taken up by and expressed in striated muscle after direct intramuscular injection. We have developed interactive polymeric gene delivery systems that increase pDNA bioavailability to muscle cells by both protecting pDNA from nucleases and controlling the dispersion and retention of pDNA in muscle tissue.lld:pubmed
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pubmed-article:8860424pubmed:articleTitlePolyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle.lld:pubmed
pubmed-article:8860424pubmed:affiliationDepartment of Gene Delivery, GENEMEDICINE, INC., The Woodlands, Texas 7738-4248, USA.lld:pubmed
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