| pubmed-article:8853270 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0927232 | lld:lifeskim |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0005367 | lld:lifeskim |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0033727 | lld:lifeskim |
| pubmed-article:8853270 | lifeskim:mentions | umls-concept:C0006353 | lld:lifeskim |
| pubmed-article:8853270 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8853270 | pubmed:dateCreated | 1997-1-3 | lld:pubmed |
| pubmed-article:8853270 | pubmed:abstractText | The role of bicarbonate as a hydrogen ion buffer has been investigated using the fluorescent dye BCECF in individual rat cerebellar, hippocampal and neocortical neurones maintained in culture. The steady-state intracellular pH (pHi) was estimated to be 7.07 +/- 0.05 (n = 22) in CO2-HCO3(-)-buffered media. Buffering power (beta) estimated from the addition and removal of weak bases was ca 10 mM (pH unit)-1 and was found to be similar in both CO2-HCO3(-)- and Hepes-buffered media. The membrane-permeant carbonic anhydrase inhibitor, acetazolamide (10-20 microM), did not affect estimates of beta. The results indicate that CO2-HCO3- does not act as an open buffer system in these neurones. | lld:pubmed |
| pubmed-article:8853270 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8853270 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8853270 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8853270 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8853270 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8853270 | pubmed:issn | 0958-0670 | lld:pubmed |
| pubmed-article:8853270 | pubmed:author | pubmed-author:RichardsC DCD | lld:pubmed |
| pubmed-article:8853270 | pubmed:author | pubmed-author:PocockGG | lld:pubmed |
| pubmed-article:8853270 | pubmed:author | pubmed-author:AmosB JBJ | lld:pubmed |
| pubmed-article:8853270 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8853270 | pubmed:volume | 81 | lld:pubmed |
| pubmed-article:8853270 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8853270 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8853270 | pubmed:pagination | 623-32 | lld:pubmed |
| pubmed-article:8853270 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8853270 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8853270 | pubmed:articleTitle | On the role of bicarbonate as a hydrogen ion buffer in rat CNS neurones. | lld:pubmed |
| pubmed-article:8853270 | pubmed:affiliation | Department of Physiology, Royal Free Hospital School of Medicine, London, UK. | lld:pubmed |
| pubmed-article:8853270 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8853270 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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