| pubmed-article:8840975 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8840975 | lifeskim:mentions | umls-concept:C0033325 | lld:lifeskim |
| pubmed-article:8840975 | lifeskim:mentions | umls-concept:C0853879 | lld:lifeskim |
| pubmed-article:8840975 | lifeskim:mentions | umls-concept:C0302600 | lld:lifeskim |
| pubmed-article:8840975 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:8840975 | lifeskim:mentions | umls-concept:C0332448 | lld:lifeskim |
| pubmed-article:8840975 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:8840975 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:8840975 | pubmed:dateCreated | 1996-11-4 | lld:pubmed |
| pubmed-article:8840975 | pubmed:abstractText | Angiogenesis is a key process in tumor growth and metastasis and is a major independent prognostic factor in breast cancer. A range of cytokines stimulate the tumor neovasculature, and tumor-associated macrophages have been shown recently to produce several important angiogenic factors. We have quantified macrophage infiltration using Chalkley count morphometry in a series of invasive breast carcinomas to investigate the relationship between tumor-associated macrophage infiltration and tumor angiogenesis, and prognosis. There was a significant positive correlation between high vascular grade and increased macrophage index (P = 0.03), and a strong relationship was observed between increased macrophage counts and reduced relapse-free survival (P = 0.006) and reduced overall survival (P = 0.004) as an independent prognostic variable. These data indicate a role for macrophages in angiogenesis and prognosis in breast cancer and that this cell type may represent an important target for immunoinhibitory therapy in breast cancer. | lld:pubmed |
| pubmed-article:8840975 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8840975 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8840975 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8840975 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8840975 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8840975 | pubmed:issn | 0008-5472 | lld:pubmed |
| pubmed-article:8840975 | pubmed:author | pubmed-author:LewisC ECE | lld:pubmed |
| pubmed-article:8840975 | pubmed:author | pubmed-author:WhitehouseRR | lld:pubmed |
| pubmed-article:8840975 | pubmed:author | pubmed-author:NovoSS | lld:pubmed |
| pubmed-article:8840975 | pubmed:author | pubmed-author:HarrisA LAL | lld:pubmed |
| pubmed-article:8840975 | pubmed:author | pubmed-author:ClarkeJJ | lld:pubmed |
| pubmed-article:8840975 | pubmed:author | pubmed-author:GreenallMM | lld:pubmed |
| pubmed-article:8840975 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8840975 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:8840975 | pubmed:volume | 56 | lld:pubmed |
| pubmed-article:8840975 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8840975 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8840975 | pubmed:pagination | 4625-9 | lld:pubmed |
| pubmed-article:8840975 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:meshHeading | pubmed-meshheading:8840975-... | lld:pubmed |
| pubmed-article:8840975 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8840975 | pubmed:articleTitle | Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. | lld:pubmed |
| pubmed-article:8840975 | pubmed:affiliation | Imperial Cancer Research Fund Molecular Oncology Laboratory, University of Oxford Institute of Molecular Medicine, England. | lld:pubmed |
| pubmed-article:8840975 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8840975 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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