| pubmed-article:8806656 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0206190 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0033681 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C1155312 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C2348205 | lld:lifeskim |
| pubmed-article:8806656 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:8806656 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8806656 | pubmed:dateCreated | 1996-10-22 | lld:pubmed |
| pubmed-article:8806656 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8806656 | pubmed:abstractText | Using differential screening we have cloned a cDNA encoding a novel oxidative stress protein designated A170 from murine peritoneal macrophages. It has a Zn-finger domain, a PEST domain and several potential phosphorylation sites for kinases. Treatments with oxidative stress agents such as diethyl maleate and paraquat increased a 2.0-kilobase A170 mRNA about twofold in the macrophages after 12 hours in culture. However, H2O2 or glucose/glucose oxidase did not increase the level of the A170 mRNA. Using an A170-specific antibody we have detected in the macrophages a 60-kDa protein that was induced 5 to 10 hours after the addition of the oxidative stress agents. A search of sequence databases revealed that the A170 protein is roughly 90% identical to a human protein that binds to the Src homology 2 domain of the T-cell-specific tyrosine kinase p56lck. These features suggest that the A170 protein plays a significant role in oxidative stress-responsive signal transduction in macrophages. | lld:pubmed |
| pubmed-article:8806656 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8806656 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8806656 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8806656 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8806656 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:8806656 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8806656 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8806656 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:8806656 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:8806656 | pubmed:author | pubmed-author:YoshidaHH | lld:pubmed |
| pubmed-article:8806656 | pubmed:author | pubmed-author:IshiiTT | lld:pubmed |
| pubmed-article:8806656 | pubmed:author | pubmed-author:YukiKK | lld:pubmed |
| pubmed-article:8806656 | pubmed:author | pubmed-author:YanagawaTT | lld:pubmed |
| pubmed-article:8806656 | pubmed:author | pubmed-author:BannaiSS | lld:pubmed |
| pubmed-article:8806656 | pubmed:author | pubmed-author:SeitzSS | lld:pubmed |
| pubmed-article:8806656 | pubmed:author | pubmed-author:KawaneTT | lld:pubmed |
| pubmed-article:8806656 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8806656 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:8806656 | pubmed:volume | 226 | lld:pubmed |
| pubmed-article:8806656 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8806656 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8806656 | pubmed:pagination | 456-60 | lld:pubmed |
| pubmed-article:8806656 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:8806656 | pubmed:meshHeading | pubmed-meshheading:8806656-... | lld:pubmed |
| pubmed-article:8806656 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8806656 | pubmed:articleTitle | Murine peritoneal macrophages induce a novel 60-kDa protein with structural similarity to a tyrosine kinase p56lck-associated protein in response to oxidative stress. | lld:pubmed |
| pubmed-article:8806656 | pubmed:affiliation | Department of Biochemistry, University of Tsukuba, Ibaraki, Japan. | lld:pubmed |
| pubmed-article:8806656 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8806656 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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