Linked Life Data

8805590

Source:http://linkedlifedata.com/resource/pubmed/id/8805590

Statements in which the resource exists.
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pubmed-article:8805590pubmed:abstractTextS100B (S100beta) is a member of the S100 family of small calcium-binding proteins: members of this family contain two helix-loop-helix calcium-binding motifs and interact with a wide range of proteins involved mainly in the cytoskeleton and cell proliferation. S100B is a neurite-extension factor and levels of S100B are elevated in the brains of patients with Alzheimer's disease or Down's syndrome: the pattern of S100B overexpression in Alzheimer's disease correlates with the pattern of neuritic-plaque formation. Identification of a growing class of S100 proteins and the likely neurochemical importance of S100B make the determination of the structure of S100B of interest.lld:pubmed
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pubmed-article:8805590pubmed:dateRevised2010-3-24lld:pubmed
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pubmed-article:8805590pubmed:articleTitleThe solution structure of the bovine S100B protein dimer in the calcium-free state.lld:pubmed
pubmed-article:8805590pubmed:affiliationDepartment of Biochemistry and Biological NMR Centre, Adrian Building, University of Leicester, Leicester, LE1 7RH, UK. pmk@le.ac.uklld:pubmed
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pubmed-article:8805590pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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