pubmed-article:8789275 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8789275 | lifeskim:mentions | umls-concept:C0028128 | lld:lifeskim |
pubmed-article:8789275 | lifeskim:mentions | umls-concept:C0175518 | lld:lifeskim |
pubmed-article:8789275 | lifeskim:mentions | umls-concept:C0206309 | lld:lifeskim |
pubmed-article:8789275 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
pubmed-article:8789275 | lifeskim:mentions | umls-concept:C0205099 | lld:lifeskim |
pubmed-article:8789275 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
pubmed-article:8789275 | lifeskim:mentions | umls-concept:C0335218 | lld:lifeskim |
pubmed-article:8789275 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:8789275 | pubmed:dateCreated | 1996-10-23 | lld:pubmed |
pubmed-article:8789275 | pubmed:abstractText | An anatomical basis was sought for the postulated roles of nitric oxide (NO) as a labile transcellular messenger in the dorsal vagal complex (NTS-X). The diaphorase activity of NO synthase was used as a marker of neurons in NTS-X that are presumed to convert L-arginine to L-citrulline and NO. Nicotinamide adenine dinucleotide phosphate diaphorase (NADPHd) staining patterns in the nucleus tractus solitarii (NTS) were spatially related to terminal sites of primary visceral afferents from 1) orosensory receptors (e.g., rostral-central nucleus); 2) soft palate, pharynx, larynx, and tracheobronchial tree (e.g., dorsal, intermediate, and interstitial nuclei); 3) esophagus (nucleus centralis); 4) stomach (nucleus gelatinosus); 5) hepatic and coeliac nerves (nucleus subpostrema); and 6) carotid body and baroreceptors (medial commissural and dorsal-lateral nuclei). Primary visceral afferents were identified as sources of NADPHd-stained fiber plexuses in the NTS-X based on three findings: 1) the presence of NADPHd in nodose ganglion cells with morphological features of first-order sensory relay neurons; 2) retrograde transport of Fluoro-Gold (FG) or cholera toxin B (CT-B) from NTS-X to NADPHd-positive nodose ganglion neurons; and 3) striking reductions of NADPHd-stained processes within primary vagal projection fields ipsilateral to unilateral nodose ganglionectomy. A central origin of NADPHd-stained processes in NTS-X was identified in the medial parvicellular subdivision of the paraventricular hypothalamic nucleus. We conclude that NO of peripheral and central origin may modulate viscerosensory signal processing in the NTS-X and autonomic reflex function. | lld:pubmed |
pubmed-article:8789275 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8789275 | pubmed:language | eng | lld:pubmed |
pubmed-article:8789275 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8789275 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8789275 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8789275 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:8789275 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8789275 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8789275 | pubmed:month | Jan | lld:pubmed |
pubmed-article:8789275 | pubmed:issn | 0021-9967 | lld:pubmed |
pubmed-article:8789275 | pubmed:author | pubmed-author:AnwarMM | lld:pubmed |
pubmed-article:8789275 | pubmed:author | pubmed-author:OtakeKK | lld:pubmed |
pubmed-article:8789275 | pubmed:author | pubmed-author:NICKW VWV | lld:pubmed |
pubmed-article:8789275 | pubmed:author | pubmed-author:RuggieroD ADA | lld:pubmed |
pubmed-article:8789275 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8789275 | pubmed:day | 1 | lld:pubmed |
pubmed-article:8789275 | pubmed:volume | 364 | lld:pubmed |
pubmed-article:8789275 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8789275 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8789275 | pubmed:pagination | 51-67 | lld:pubmed |
pubmed-article:8789275 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:8789275 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8789275 | pubmed:articleTitle | Central and primary visceral afferents to nucleus tractus solitarii may generate nitric oxide as a membrane-permeant neuronal messenger. | lld:pubmed |
pubmed-article:8789275 | pubmed:affiliation | Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA. | lld:pubmed |
pubmed-article:8789275 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8789275 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:8789275 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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