pubmed-article:8752830 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8752830 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:8752830 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:8752830 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:8752830 | lifeskim:mentions | umls-concept:C1815389 | lld:lifeskim |
pubmed-article:8752830 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:8752830 | pubmed:dateCreated | 1996-12-13 | lld:pubmed |
pubmed-article:8752830 | pubmed:abstractText | Inflammatory skin disorders such as psoriasis show a preferential epidermal infiltration of neutrophils and T lymphocytes. This observation raises a question as to which factors determine the appearance and composition of leukocyte tissue infiltrations. Previously, we described a low molecular mass calcium-binding protein (psoriasin, molecular mass 11,457 Da, pI 6.77) belonging to the S1OO family that is highly upregulated in psoriatic keratinocytes and whose expression patterns implied a role in the inflammatory response. Here we report that human psoriasin is a potent and selective chemotactic inflammatory protein for CD4+ T lymphocytes and neutrophils at concentrations of about 10(-11) M. Psoriasin is not structurally related to the alpha or the beta chemokine subfamilies or to lymphotactin, a member of a newly described class of chemokines. Thus, we have observed a chemotactic protein outside the chemokine subfamilies that could be an important new inflammatory mediator. | lld:pubmed |
pubmed-article:8752830 | pubmed:language | eng | lld:pubmed |
pubmed-article:8752830 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8752830 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8752830 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8752830 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8752830 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8752830 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8752830 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8752830 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8752830 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8752830 | pubmed:month | Jul | lld:pubmed |
pubmed-article:8752830 | pubmed:issn | 0022-202X | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:RasmussenH... | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:Thestrup-Pede... | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:MadsenPP | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:CelisJ EJE | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:HonoréBB | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:GesserBB | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:JinquanTT | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:LarsenC GCG | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:EtzerodtMM | lld:pubmed |
pubmed-article:8752830 | pubmed:author | pubmed-author:VorumHH | lld:pubmed |
pubmed-article:8752830 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8752830 | pubmed:volume | 107 | lld:pubmed |
pubmed-article:8752830 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8752830 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8752830 | pubmed:pagination | 5-10 | lld:pubmed |
pubmed-article:8752830 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:meshHeading | pubmed-meshheading:8752830-... | lld:pubmed |
pubmed-article:8752830 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8752830 | pubmed:articleTitle | Psoriasin: a novel chemotactic protein. | lld:pubmed |
pubmed-article:8752830 | pubmed:affiliation | Department of Dermatology, Marselisborg Hospital, Aarhus, Denmark. | lld:pubmed |
pubmed-article:8752830 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8752830 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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