| pubmed-article:8733698 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8733698 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:8733698 | lifeskim:mentions | umls-concept:C0005961 | lld:lifeskim |
| pubmed-article:8733698 | lifeskim:mentions | umls-concept:C0023516 | lld:lifeskim |
| pubmed-article:8733698 | lifeskim:mentions | umls-concept:C0206161 | lld:lifeskim |
| pubmed-article:8733698 | lifeskim:mentions | umls-concept:C1522577 | lld:lifeskim |
| pubmed-article:8733698 | lifeskim:mentions | umls-concept:C0681842 | lld:lifeskim |
| pubmed-article:8733698 | lifeskim:mentions | umls-concept:C1262018 | lld:lifeskim |
| pubmed-article:8733698 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8733698 | pubmed:dateCreated | 1996-11-6 | lld:pubmed |
| pubmed-article:8733698 | pubmed:abstractText | Allogeneic BMT using a non-genotypically HLA-identical donor may be curative for children suffering from lethal haematological diseases, who lack a genotypically HLA-identical donor. Unfortunately, graft failures are often seen, especially after T cell depletion of the graft. We studied whether untimely decreased counts of leucocytes and reticulocytes in peripheral blood might predict graft failure at an early stage. Fifty-five recipients of a non-genotypically HLA-identical BM graft were included in the study; data from these children were compared with those of 77 recipients of a genotypically HLA-identical BM graft. Time-related reference values of peripheral blood leucocyte and reticulocyte counts were established in graft recipients with proven donor-origin recovery after BMT. Graft failure after nonHLA-identical BMT was observed in 16 out of 55 children (29%) and after HLA-identical BMT in one out of 77 (1.3%). With respect to early graft failure, the predictive value of granulocyte numbers falling below the lower limit of the reference values and a rapid decline of reticulocyte numbers after their appearance in peripheral blood was 100% (95% confidence intervals of 83-100% and of 80-100%, respectively). Early immunosuppressive intervention was applied in six patients and was successful in three of them. | lld:pubmed |
| pubmed-article:8733698 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8733698 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8733698 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8733698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8733698 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8733698 | pubmed:month | May | lld:pubmed |
| pubmed-article:8733698 | pubmed:issn | 0268-3369 | lld:pubmed |
| pubmed-article:8733698 | pubmed:author | pubmed-author:VossenJ MJM | lld:pubmed |
| pubmed-article:8733698 | pubmed:author | pubmed-author:HaraldssonAA | lld:pubmed |
| pubmed-article:8733698 | pubmed:author | pubmed-author:Van den... | lld:pubmed |
| pubmed-article:8733698 | pubmed:author | pubmed-author:Van TolM JMJ | lld:pubmed |
| pubmed-article:8733698 | pubmed:author | pubmed-author:GerritsenE... | lld:pubmed |
| pubmed-article:8733698 | pubmed:author | pubmed-author:StamE DED | lld:pubmed |
| pubmed-article:8733698 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8733698 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:8733698 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8733698 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8733698 | pubmed:pagination | 781-7 | lld:pubmed |
| pubmed-article:8733698 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:meshHeading | pubmed-meshheading:8733698-... | lld:pubmed |
| pubmed-article:8733698 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8733698 | pubmed:articleTitle | Follow-up of leucocyte and reticulocyte counts for the prediction of early graft failure after non-HLA-identical BMT in children. | lld:pubmed |
| pubmed-article:8733698 | pubmed:affiliation | Department of Paediatrics, Leiden University Hospital, The Netherlands. | lld:pubmed |
| pubmed-article:8733698 | pubmed:publicationType | Journal Article | lld:pubmed |
