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pubmed-article:8731265pubmed:abstractTextA seroepidemiologic survey was carried out in schoolchildren from public schools of the Niterói municipality, state of Rio de Janeiro, Brazil, after a period of sequential epidemics by dengue virus type 1 and 2 (DEN-1 and DEN-2). 450 blood samples were obtained by fingertip puncture and collected on filter paper discs. The hemagglutination inhibition (HAI) test was carried out using DEN-1 and DEN-2 antigens. HAI titres were demonstrated in 66% (297/450) of the sera and the geometric means of the titres were 1/182 and 1/71 for DEN-1 and DEN-2, respectively. Secondary infections were observed in 61% (181/297) of positive cases. Among these, 75% (135/181) were under fifteen years old. No dengue haemorrhagic fever (DHF) was reported in these children. Asymptomatic or oligosymptomatic infections were detected in 56% of the studied population. The absolute and relative frequencies of positive tests by age group and sex did not evidence statistically significant difference. The number of individuals infected probably produced a immunologic barrier responsible for the non occurrence of dengue epidemic in the latter years.lld:pubmed
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pubmed-article:8731265pubmed:pagination517-21lld:pubmed
pubmed-article:8731265pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:8731265pubmed:articleTitleSecondary dengue infection in schoolchildren in a dengue endemic area in the state of Rio de Janeiro, Brazil.lld:pubmed
pubmed-article:8731265pubmed:affiliationDepartamento de Clínica Médica, Universidade Federal de Mato Grosso do Sul, Rio de Janeiro, Brazil.lld:pubmed
pubmed-article:8731265pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8731265pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed