| pubmed-article:8726861 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8726861 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8726861 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:8726861 | lifeskim:mentions | umls-concept:C1281743 | lld:lifeskim |
| pubmed-article:8726861 | lifeskim:mentions | umls-concept:C0008625 | lld:lifeskim |
| pubmed-article:8726861 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:8726861 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:8726861 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8726861 | pubmed:dateCreated | 1997-3-25 | lld:pubmed |
| pubmed-article:8726861 | pubmed:abstractText | The relationship between the survival of the human preimplantation embryo in vitro and chromosomal abnormality was investigated by cytogenetic analysis of a total of 250 embryos of varying morphology between the pronucleate stage and the 8-cell stage. The overall incidence of chromosomal abnormality among these embryos was 49%. At the pronucleate stage (n = 46) the incidence was 65.2%, at the 2-4-cell stage (n = 126) it was 54.6%, and at the 5-8-cell stage (n = 78) it was 27.4%. Cleavage-stage embryos with poor morphology (irregular shaped blastomeres with severe extracellular fragmentation) showed a higher incidence of chromosomal abnormality (62%; 54 of 87 analysed) than those with good morphology (22.2%; 26 of 117 analysed). This study demonstrates: (i) that there is progressive loss of chromosomally-abnormal embryos during preimplantation development; and (ii) that there is an association between chromosomal abnormality and embryo morphology. | lld:pubmed |
| pubmed-article:8726861 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8726861 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8726861 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8726861 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8726861 | pubmed:issn | 1031-3613 | lld:pubmed |
| pubmed-article:8726861 | pubmed:author | pubmed-author:AlmeidaP APA | lld:pubmed |
| pubmed-article:8726861 | pubmed:author | pubmed-author:BoltonV NVN | lld:pubmed |
| pubmed-article:8726861 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8726861 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:8726861 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8726861 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8726861 | pubmed:pagination | 235-41 | lld:pubmed |
| pubmed-article:8726861 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:meshHeading | pubmed-meshheading:8726861-... | lld:pubmed |
| pubmed-article:8726861 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8726861 | pubmed:articleTitle | The relationship between chromosomal abnormality in the human preimplantation embryo and development in vitro. | lld:pubmed |
| pubmed-article:8726861 | pubmed:affiliation | Department of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry, London, UK. | lld:pubmed |
| pubmed-article:8726861 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8726861 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
