Linked Life Data

8719462

Source:http://linkedlifedata.com/resource/pubmed/id/8719462

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pubmed-article:8719462pubmed:abstractTextIntercellular reactions and cell-matrix interactions are mediated by a number of specific adhesion molecules. For the intravascular reactivity of leukocytes and thrombocytes the endothelial expression of adhesion ligand molecules is of main importance. This condition may be of special relevance for the organ-specific manifestation of immune reactions in heart and lung transplants. The question was investigated as to whether organ-specific differences exist on arterial, venous, and capillary endothelial lining cells in heart and lung transplants and whether this condition is modified during transplant rejection. Transplant biopsy specimens of 24 heart transplant recipients (n = 303) and lung transplant recipients who underwent retransplantation for rejection (n = 4), as well as normal heart (n = 7) and lung tissue (n = 4), were studied. Cell-cell adhesion molecules (intercellular adhesion molecule-1 (CD54) and -2; LFA-3; CD31; vascular cellular adhesion molecule-1; neural cellular adhesion molecule; E-/P-selectin; CD44) and cell-matrix adhesion molecules (very late antigen-1 through -6; CD51) were studied on cryostat sections by means of standard immunohistology.lld:pubmed
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pubmed-article:8719462pubmed:pagination1145-55lld:pubmed
pubmed-article:8719462pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:8719462pubmed:articleTitleDistinct expression of cell-cell and cell-matrix adhesion molecules on endothelial cells in human heart and lung transplants.lld:pubmed
pubmed-article:8719462pubmed:affiliationDepartment of Cardiovascular Surgery, University of Kiel, Germany.lld:pubmed
pubmed-article:8719462pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8719462pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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