| pubmed-article:8708576 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C0596981 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C0026237 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C0030054 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C0699914 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C1561604 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C0243163 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C1710236 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C1999230 | lld:lifeskim |
| pubmed-article:8708576 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
| pubmed-article:8708576 | pubmed:issue | Pt 8 | lld:pubmed |
| pubmed-article:8708576 | pubmed:dateCreated | 1996-9-12 | lld:pubmed |
| pubmed-article:8708576 | pubmed:abstractText | This paper quantifies the structures involved in the transport and oxidation of carbohydrates and fatty acids within the muscle cell. The structural capacity is measured on whole-body random samples of the musculature of dogs and pygmy goats and compared with maximal rates of oxygen consumption and substrate oxidation. Comparing dogs and goats of the same body size provided a 1.55-fold difference in the maximal rate of oxidation when related to muscle mass. As in previous studies, we found that the volume of mitochondria was approximately proportional to aerobic capacity. The maximal glucose flux from intracellular stores to mitochondria is 1.6 times greater in the dog than in the goat; we find that the amount of glycogen stored in the muscle cells is 4.2 times as great in the dog, but part of the intracellular glycogen pool is used for anaerobic rather than for oxidative metabolism. The maximal fatty acid flux from intracellular stores to mitochondria is 1.5 times larger in the dog, and the amount of lipid stored is 2.3 times as great in the dog. Every lipid droplet is in direct contact with the outer membrane of a mitochondrion and the contact surface area is 3.6 times greater in the dog than in the goat. Additional measurements are needed to investigate the role of structural limitation at this step. The amount of substrates stored intracellularly in the muscle cells of the dog is about twice as much as would match the differences in the maximal rates of utilization. This allows the endurance-specialized dogs to run for longer periods at higher rates of oxidation. | lld:pubmed |
| pubmed-article:8708576 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8708576 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8708576 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8708576 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8708576 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8708576 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8708576 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8708576 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8708576 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:8708576 | pubmed:issn | 0022-0949 | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:TaylorC RCR | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:WeibelE RER | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:ClaassenHH | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:WeberJ MJM | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:BilleterRR | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:HoppelerHH | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:VockRR | lld:pubmed |
| pubmed-article:8708576 | pubmed:author | pubmed-author:DUCPP | lld:pubmed |
| pubmed-article:8708576 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8708576 | pubmed:volume | 199 | lld:pubmed |
| pubmed-article:8708576 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8708576 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8708576 | pubmed:pagination | 1689-97 | lld:pubmed |
| pubmed-article:8708576 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8708576 | pubmed:meshHeading | pubmed-meshheading:8708576-... | lld:pubmed |
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| pubmed-article:8708576 | pubmed:meshHeading | pubmed-meshheading:8708576-... | lld:pubmed |
| pubmed-article:8708576 | pubmed:meshHeading | pubmed-meshheading:8708576-... | lld:pubmed |
| pubmed-article:8708576 | pubmed:meshHeading | pubmed-meshheading:8708576-... | lld:pubmed |
| pubmed-article:8708576 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8708576 | pubmed:articleTitle | Design of the oxygen and substrate pathways. VI. structural basis of intracellular substrate supply to mitochondria in muscle cells. | lld:pubmed |
| pubmed-article:8708576 | pubmed:affiliation | Department of Anatomy, University of Berne, Switzerland. | lld:pubmed |
| pubmed-article:8708576 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8708576 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8708576 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:8708576 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8708576 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8708576 | lld:pubmed |
