| pubmed-article:8707416 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8707416 | lifeskim:mentions | umls-concept:C0032556 | lld:lifeskim |
| pubmed-article:8707416 | lifeskim:mentions | umls-concept:C0027651 | lld:lifeskim |
| pubmed-article:8707416 | lifeskim:mentions | umls-concept:C0206745 | lld:lifeskim |
| pubmed-article:8707416 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:8707416 | lifeskim:mentions | umls-concept:C0205173 | lld:lifeskim |
| pubmed-article:8707416 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
| pubmed-article:8707416 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8707416 | pubmed:dateCreated | 1996-9-10 | lld:pubmed |
| pubmed-article:8707416 | pubmed:abstractText | CD4-/- or CD8-/- single knockout as well as CD4-/-8-/- double knockout mice were infected with polyoma virus as newborns or 1 week after birth. The animals were followed for tumor development and virus persistence. Double knockout mice developed tumors at a higher incidence (29%) than either the CD8-/- or CD4-/- single knockout mice (11% and 2%, respectively). Persistence of polyoma virus was examined by PCR in one third of all animals included in the study. Seven of the 17 CD4-/-8-/- double knockout mice gave positive evidence of virus persistence up to 6 months p.i. where virus DNA was present in most organs. Corresponding tests in single knockout mice gave positive results of persistent viral DNA in 2 of the 19 CD8-/-and 2 of the 7 CD4-/-mice. In the single knockout mice polyoma DNA could only be detected in a more limited variety of organs compared to the double knockouts. | lld:pubmed |
| pubmed-article:8707416 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8707416 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8707416 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8707416 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8707416 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8707416 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8707416 | pubmed:issn | 0020-7136 | lld:pubmed |
| pubmed-article:8707416 | pubmed:author | pubmed-author:KleinGG | lld:pubmed |
| pubmed-article:8707416 | pubmed:author | pubmed-author:DalianisTT | lld:pubmed |
| pubmed-article:8707416 | pubmed:author | pubmed-author:BerkaVV | lld:pubmed |
| pubmed-article:8707416 | pubmed:author | pubmed-author:WenTT | lld:pubmed |
| pubmed-article:8707416 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8707416 | pubmed:day | 29 | lld:pubmed |
| pubmed-article:8707416 | pubmed:volume | 67 | lld:pubmed |
| pubmed-article:8707416 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8707416 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8707416 | pubmed:pagination | 405-8 | lld:pubmed |
| pubmed-article:8707416 | pubmed:dateRevised | 2007-7-24 | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
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| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
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| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:meshHeading | pubmed-meshheading:8707416-... | lld:pubmed |
| pubmed-article:8707416 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8707416 | pubmed:articleTitle | Polyoma tumor development in neonatally polyoma-virus-infected CD4-/- and CD8-/- single knockout and CD4-/-8-/- double knockout mice. | lld:pubmed |
| pubmed-article:8707416 | pubmed:affiliation | Division of Clinical Virology, Karolinska Institute, Huddinge University Hospital, Sweden. | lld:pubmed |
| pubmed-article:8707416 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8707416 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8707416 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:12504 | entrezgene:pubmed | pubmed-article:8707416 | lld:entrezgene |
| entrez-gene:12525 | entrezgene:pubmed | pubmed-article:8707416 | lld:entrezgene |
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