| pubmed-article:8678740 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C0155626 | lld:lifeskim |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C0011900 | lld:lifeskim |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C1305957 | lld:lifeskim |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C1522609 | lld:lifeskim |
| pubmed-article:8678740 | lifeskim:mentions | umls-concept:C1554112 | lld:lifeskim |
| pubmed-article:8678740 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8678740 | pubmed:dateCreated | 1996-8-13 | lld:pubmed |
| pubmed-article:8678740 | pubmed:abstractText | Immunoenzymatic assay (IEMA) of human cardiac Troponin I (TnI c) was used in patients admitted to the coronary care unit with acute myocardial infarction (AMI). TnI c was detected in all patients with AMI. The detection of TnI c was earlier after the onset of pain (4.5 +/- 2.3 hours) than that of CKMB activity (6.3 +/- 3.6 hours), p = 0.003. The kinetics of TnI c are usually monophasic and parallel to that of CKMB activity. The peak value occurs 12.2 +/- 4.6 hours and 15.8 +/- 9.0 hours after the onset of pain in patients treated by thrombolysis. The TnI c disappears from the plasma between 5 and 9 days after the onset of pain, later than CKMB activity (p = 0.0001). In 49 patients admitted for AMI treated by thrombolysis, the comparative sensitivities of TnI c (threshold: 0.1 ng/ml) and of CKMB activity (threshold: 15 IU/l; CK > or = 100 Ul/l) were, at the first sampling on admission, 61% and 22% respectively (p = 0.0002) (average interval from onset of pain to first blood sampling: 3.4 +/- 1.3 hours). TnI c was not detected in the plasma of 145 normal subjects nor in any of the 6 patients with severe muscular trauma or rhabdomyolosis (specificity: 100%). This IEMA is a specific and a sensitive method of diagnosing acute and subacute myocardial infarction. It is ideal for the detection of myocardial necrosis in complex clinical situations when the usual enzymatic markers may be ineffective. | lld:pubmed |
| pubmed-article:8678740 | pubmed:language | fre | lld:pubmed |
| pubmed-article:8678740 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8678740 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8678740 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:8678740 | pubmed:issn | 0003-9683 | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:PazOO | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:LaneJ MJM | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:BeckLL | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:LarueCC | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:BertinchantJ... | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:CalzolariCC | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:PaolucciFF | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:TrinquierSS | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:BougesSS | lld:pubmed |
| pubmed-article:8678740 | pubmed:author | pubmed-author:PernelII | lld:pubmed |
| pubmed-article:8678740 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8678740 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:8678740 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8678740 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8678740 | pubmed:pagination | 63-8 | lld:pubmed |
| pubmed-article:8678740 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:8678740 | pubmed:meshHeading | pubmed-meshheading:8678740-... | lld:pubmed |
| pubmed-article:8678740 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8678740 | pubmed:articleTitle | [Value of human cardiac troponin I determination in the diagnosis of acute myocardial infarction]. | lld:pubmed |
| pubmed-article:8678740 | pubmed:affiliation | Service de cardiologie, ERIA Diagnostics Pasteur, Marnes-La-Coquette. | lld:pubmed |
| pubmed-article:8678740 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8678740 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8678740 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:8678740 | pubmed:publicationType | Multicenter Study | lld:pubmed |
