| pubmed-article:8676541 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8676541 | lifeskim:mentions | umls-concept:C0024660 | lld:lifeskim |
| pubmed-article:8676541 | lifeskim:mentions | umls-concept:C0027061 | lld:lifeskim |
| pubmed-article:8676541 | lifeskim:mentions | umls-concept:C0086045 | lld:lifeskim |
| pubmed-article:8676541 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:8676541 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:8676541 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:8676541 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:8676541 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8676541 | pubmed:dateCreated | 1996-8-14 | lld:pubmed |
| pubmed-article:8676541 | pubmed:abstractText | A change in muscle length significantly alters the developed tension in mammalian cardiac muscle compared to that in skeletal muscle fibers. The intracellular mechanisms related to the length-dependent change in developed tension have been studied using Ca2+ indicators in intact preparations; a cross-bridge-dependent change in the affinity of troponin-C for Ca2+ is a possible mechanism. This hypothesis is further supported by the measurement of Ca2+ bound to troponin-C in skinned preparations. The molecular mechanism of the cross-bridge-dependent change in the affinity of troponin-C for Ca2+ is not fully understood although the studies which employ the substitution of troponin-C in skinned preparations, transgenic animals and in an animal model with heart disease have been performed. We reviewed the current studies by analyzing the intracellular mechanism responsible for the length-dependent change in tension development in mammalian cardiac muscle. | lld:pubmed |
| pubmed-article:8676541 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8676541 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8676541 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8676541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8676541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8676541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8676541 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8676541 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:8676541 | pubmed:issn | 0021-4868 | lld:pubmed |
| pubmed-article:8676541 | pubmed:author | pubmed-author:KuriharaSS | lld:pubmed |
| pubmed-article:8676541 | pubmed:author | pubmed-author:KomukaiKK | lld:pubmed |
| pubmed-article:8676541 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8676541 | pubmed:volume | 37 | lld:pubmed |
| pubmed-article:8676541 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8676541 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8676541 | pubmed:pagination | 143-52 | lld:pubmed |
| pubmed-article:8676541 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:meshHeading | pubmed-meshheading:8676541-... | lld:pubmed |
| pubmed-article:8676541 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8676541 | pubmed:articleTitle | Cross-bridge-dependent changes in the intracellular Ca2+ concentration in mammalian cardiac muscles. | lld:pubmed |
| pubmed-article:8676541 | pubmed:affiliation | Department of Physiology, Jikei University School of Medicine, Tokyo, Japan. | lld:pubmed |
| pubmed-article:8676541 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8676541 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:8676541 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
