| pubmed-article:8669413 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C0008377 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C1708335 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C0008731 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C1325761 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C0700364 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C0376674 | lld:lifeskim |
| pubmed-article:8669413 | lifeskim:mentions | umls-concept:C1264633 | lld:lifeskim |
| pubmed-article:8669413 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8669413 | pubmed:dateCreated | 1996-8-8 | lld:pubmed |
| pubmed-article:8669413 | pubmed:abstractText | This study examined the appearance of dietary cholesterol in the chylomicron fraction (chylomicrons plus chylomicron remnants) and whole plasma in healthy normolipidemic subjects during a 0-7-h postprandial period. Six adult males were given two diet sequences in random order: a low-fiber diet (standard Western diet for 14 d) followed by a labeled low-fiber test meal or a fiber-supplemented diet (40 g oat bran/d for 14 d) followed by a labeled oat bran (40 g) test meal. The test meals provided 192.5 mg cholesterol, including 80.1 mg octadeuterated cholesterol. Fasting and hourly postmeal blood samples were obtained for 7 h. Isotopic cholesterol ratios [tracer:(tracer+native cholesterol)] were determined by gas chromatography-mass spectrometry. Chylomicron triacylglycerol and cholesterol concentrations peaked after 2-3 h and returned to baseline after 7 h. After the low-fiber test meal, the isotopic cholesterol ratio continuously increased until 7 h in the chylomicron fraction (4.2 +/- 1.2 x 10(-3)) and whole plasma (1.04 +/- 0.39 x 10(-3)). At 7 h postprandial, the maximum dietary cholesterol concentration in the chylomicron fraction and plasma cholesterol was 1 in 99 and 1 in 397 cholesterol molecules, respectively. No marked differences were obtained after the high-fiber sequence compared with the low-fiber one; there was a comparable isotopic cholesterol ratio and concentration in the chylomicron fraction and a slightly lower (-44%, P < 0.10) 0-7 h area under the curve whole-plasma deuterated cholesterol concentration. Thus, dietary cholesterol supplied as a single meal does not simultaneously appear in the chylomicron fraction postprandially with endogenous cholesterol and triacylglycerols and fiber feeding does not markedly alter this process in healthy normolipidemic humans. | lld:pubmed |
| pubmed-article:8669413 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8669413 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8669413 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:8669413 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8669413 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8669413 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8669413 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8669413 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8669413 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8669413 | pubmed:issn | 0002-9165 | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:PauliA MAM | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:LafontHH | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:LaironDD | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:DuboisCC | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:FerezouJJ | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:BernardP MPM | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:PortugalHH | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:ArmandMM | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:BecueTT | lld:pubmed |
| pubmed-article:8669413 | pubmed:author | pubmed-author:BeaumierGG | lld:pubmed |
| pubmed-article:8669413 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8669413 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:8669413 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8669413 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8669413 | pubmed:pagination | 47-52 | lld:pubmed |
| pubmed-article:8669413 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:meshHeading | pubmed-meshheading:8669413-... | lld:pubmed |
| pubmed-article:8669413 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8669413 | pubmed:articleTitle | Postprandial appearance of dietary deuterated cholesterol in the chylomicron fraction and whole plasma in healthy subjects. | lld:pubmed |
| pubmed-article:8669413 | pubmed:affiliation | Unité 130-INSERM (Institut National de la Santé et de la Recherche Medicale), Marseille, France. | lld:pubmed |
| pubmed-article:8669413 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8669413 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:8669413 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:8669413 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
