pubmed-article:8641812 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8641812 | lifeskim:mentions | umls-concept:C0521009 | lld:lifeskim |
pubmed-article:8641812 | lifeskim:mentions | umls-concept:C0121772 | lld:lifeskim |
pubmed-article:8641812 | lifeskim:mentions | umls-concept:C0032594 | lld:lifeskim |
pubmed-article:8641812 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
pubmed-article:8641812 | lifeskim:mentions | umls-concept:C0001721 | lld:lifeskim |
pubmed-article:8641812 | lifeskim:mentions | umls-concept:C1510802 | lld:lifeskim |
pubmed-article:8641812 | lifeskim:mentions | umls-concept:C2911648 | lld:lifeskim |
pubmed-article:8641812 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:8641812 | pubmed:dateCreated | 1996-7-16 | lld:pubmed |
pubmed-article:8641812 | pubmed:abstractText | Since immunization of infants with conjugated Haemophilus influenzae type b (Hib) capsular polysaccharide (PS) vaccines results in a reduction of colonization, we determined the inhibitory effect of anti-Hib PS on two steps in the colonization, i.e., adherence of H. influenzae to nasopharyngeal epithelium and bacterial growth. Monoclonal antibody (MAb) E117-5 specific for Hib PS inhibited at a concentration of at least 80 microg/ml in vitro the adherence of Hib strain 770235f+b+ to oropharyngeal epithelial cells by 50% (P <, 0.02), but this MAb and sera from children immunized with Hib PS conjugate vaccine (n = 10) were not inhibitory in final dilutions containing up to 20 microg of anti-Hib PS per ml. The growth of Hib strain 770235f+b+ did completely stop in the presence of 5 microg of anti-Hib PS MAb E117-5 per ml and human sera with an anti-Hib PS concentration of 2 microg/ml or more, in contrast to the growth of the nonencapsular variant strain 770235f+b0. | lld:pubmed |
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pubmed-article:8641812 | pubmed:language | eng | lld:pubmed |
pubmed-article:8641812 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8641812 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:8641812 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8641812 | pubmed:month | Mar | lld:pubmed |
pubmed-article:8641812 | pubmed:issn | 0019-9567 | lld:pubmed |
pubmed-article:8641812 | pubmed:author | pubmed-author:DankertJJ | lld:pubmed |
pubmed-article:8641812 | pubmed:author | pubmed-author:KäyhtyHH | lld:pubmed |
pubmed-article:8641812 | pubmed:author | pubmed-author:van MarleJJ | lld:pubmed |
pubmed-article:8641812 | pubmed:author | pubmed-author:van AlphenLL | lld:pubmed |
pubmed-article:8641812 | pubmed:author | pubmed-author:EijkPP | lld:pubmed |
pubmed-article:8641812 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8641812 | pubmed:volume | 64 | lld:pubmed |
pubmed-article:8641812 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8641812 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8641812 | pubmed:pagination | 995-1001 | lld:pubmed |
pubmed-article:8641812 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:8641812 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8641812 | pubmed:articleTitle | Antibodies to Haemophilus influenzae type b polysaccharide affect bacterial adherence and multiplication. | lld:pubmed |
pubmed-article:8641812 | pubmed:affiliation | Department of Medical Microbiology, University of Amsterdam, The Netherlands. | lld:pubmed |
pubmed-article:8641812 | pubmed:publicationType | Journal Article | lld:pubmed |
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