| pubmed-article:8631380 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8631380 | lifeskim:mentions | umls-concept:C0004897 | lld:lifeskim |
| pubmed-article:8631380 | lifeskim:mentions | umls-concept:C0025248 | lld:lifeskim |
| pubmed-article:8631380 | lifeskim:mentions | umls-concept:C0061688 | lld:lifeskim |
| pubmed-article:8631380 | lifeskim:mentions | umls-concept:C0041221 | lld:lifeskim |
| pubmed-article:8631380 | lifeskim:mentions | umls-concept:C0205349 | lld:lifeskim |
| pubmed-article:8631380 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8631380 | pubmed:dateCreated | 1996-6-28 | lld:pubmed |
| pubmed-article:8631380 | pubmed:abstractText | Tc-85, an 85-kDa surface glycoprotein specific for the trypomastigote stage of Trypanosoma cruzi, has been implicated in the invasion of host cells by the parasite. Radioactive palmitic acid was incorporated into Tc-85 immunoprecipitated from the culture medium with the H1A10 monoclonal antibody, suggesting that shedding occurs with Tc-85 bearing its GPI anchor. In contrast to the glycoprotein remaining in the parasites, the glycosylphosphatidylinositol moiety in shed Tc-85 is resistant to phosphatidylinositol phospholipase C and becomes susceptible to the enzyme following alkali treatment. An alkylglycerol was identified by thin layer chromatography of an ether extract after the enzymatic reaction. Resistance to cleavage by phospholipase C is due to fatty acid esterification of the inositol residue in shed Tc-85. This is the first example of inositol modification in anchors from a glycoprotein of Trypanosoma cruzi. | lld:pubmed |
| pubmed-article:8631380 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8631380 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8631380 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8631380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8631380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8631380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8631380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8631380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8631380 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8631380 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8631380 | pubmed:issn | 0014-4894 | lld:pubmed |
| pubmed-article:8631380 | pubmed:author | pubmed-author:ColliWW | lld:pubmed |
| pubmed-article:8631380 | pubmed:author | pubmed-author:GalliCC | lld:pubmed |
| pubmed-article:8631380 | pubmed:author | pubmed-author:AlvesM JMJ | lld:pubmed |
| pubmed-article:8631380 | pubmed:author | pubmed-author:de... | lld:pubmed |
| pubmed-article:8631380 | pubmed:author | pubmed-author:CasalO LOL | lld:pubmed |
| pubmed-article:8631380 | pubmed:author | pubmed-author:CoutoA SAS | lld:pubmed |
| pubmed-article:8631380 | pubmed:author | pubmed-author:AbuinGG | lld:pubmed |
| pubmed-article:8631380 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8631380 | pubmed:volume | 82 | lld:pubmed |
| pubmed-article:8631380 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8631380 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8631380 | pubmed:pagination | 290-7 | lld:pubmed |
| pubmed-article:8631380 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:meshHeading | pubmed-meshheading:8631380-... | lld:pubmed |
| pubmed-article:8631380 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8631380 | pubmed:articleTitle | Trypanosoma cruzi: the Tc-85 surface glycoprotein shed by trypomastigotes bears a modified glycosylphosphatidylinositol anchor. | lld:pubmed |
| pubmed-article:8631380 | pubmed:affiliation | Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Brazil. | lld:pubmed |
| pubmed-article:8631380 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8631380 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8631380 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8631380 | lld:pubmed |
