Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:8621739rdf:typepubmed:Citationlld:pubmed
pubmed-article:8621739lifeskim:mentionsumls-concept:C0206131lld:lifeskim
pubmed-article:8621739lifeskim:mentionsumls-concept:C0538990lld:lifeskim
pubmed-article:8621739lifeskim:mentionsumls-concept:C1880022lld:lifeskim
pubmed-article:8621739pubmed:issue6lld:pubmed
pubmed-article:8621739pubmed:dateCreated1996-6-19lld:pubmed
pubmed-article:8621739pubmed:abstractTextA novel membrane aminopeptidase has been identified as a major protein in vesicles from rat adipocytes containing the glucose transporter isotype Glut4. In this study we have characterized this aminopeptidase, referred to as vp165, in 3T3-L1 adipocytes. The subcellular distributions of vp165 and Glut4 were determined by immunoisolation of vesicles with antibodies against both proteins, by immunofluorescence, and by subcellular fractionation and immunoblotting. Relative amounts of vp165 at the cell surface in basal and insulin-treated cells were assayed by cell surface biotinylation. These experiments showed that vp165 and Glut4 were entirely colocalized and that vp165 increased markedly at the cell surface in response to insulin, in a way similar to Glut4. When intact cells were assayed with a novel, membrane-impermeant fluorogenic substrate for vp165, we found that insulin stimulated aminopeptidase activity at the cell surface. This observation provides direct evidence for the functional consequence of vp165 translocation.lld:pubmed
pubmed-article:8621739pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:languageenglld:pubmed
pubmed-article:8621739pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:citationSubsetIMlld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8621739pubmed:statusMEDLINElld:pubmed
pubmed-article:8621739pubmed:monthFeblld:pubmed
pubmed-article:8621739pubmed:issn0021-9258lld:pubmed
pubmed-article:8621739pubmed:authorpubmed-author:RossS ASAlld:pubmed
pubmed-article:8621739pubmed:authorpubmed-author:LienhardG EGElld:pubmed
pubmed-article:8621739pubmed:authorpubmed-author:MaiHHlld:pubmed
pubmed-article:8621739pubmed:authorpubmed-author:KellerS RSRlld:pubmed
pubmed-article:8621739pubmed:authorpubmed-author:ScottH MHMlld:pubmed
pubmed-article:8621739pubmed:authorpubmed-author:MorrisN JNJlld:pubmed
pubmed-article:8621739pubmed:authorpubmed-author:LeungW YWYlld:pubmed
pubmed-article:8621739pubmed:issnTypePrintlld:pubmed
pubmed-article:8621739pubmed:day9lld:pubmed
pubmed-article:8621739pubmed:volume271lld:pubmed
pubmed-article:8621739pubmed:ownerNLMlld:pubmed
pubmed-article:8621739pubmed:authorsCompleteYlld:pubmed
pubmed-article:8621739pubmed:pagination3328-32lld:pubmed
pubmed-article:8621739pubmed:dateRevised2011-11-17lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:meshHeadingpubmed-meshheading:8621739-...lld:pubmed
pubmed-article:8621739pubmed:year1996lld:pubmed
pubmed-article:8621739pubmed:articleTitleCharacterization of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes.lld:pubmed
pubmed-article:8621739pubmed:affiliationDepartment of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.lld:pubmed
pubmed-article:8621739pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8621739pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8621739lld:pubmed