| pubmed-article:8603376 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8603376 | lifeskim:mentions | umls-concept:C0240321 | lld:lifeskim |
| pubmed-article:8603376 | lifeskim:mentions | umls-concept:C0042056 | lld:lifeskim |
| pubmed-article:8603376 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:8603376 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:8603376 | lifeskim:mentions | umls-concept:C1527027 | lld:lifeskim |
| pubmed-article:8603376 | lifeskim:mentions | umls-concept:C0388638 | lld:lifeskim |
| pubmed-article:8603376 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:8603376 | pubmed:dateCreated | 1996-5-16 | lld:pubmed |
| pubmed-article:8603376 | pubmed:abstractText | The biological effects of dehydrodidemnin B(DDB), a novel depsipeptide isolated from Aplidium albicans, were studied on Ehrlich carcinoma growing in vivo and in primary cultures, and compared with those reported for Didemnin B (DB). Daily administration of DB or DDB (2.5 micrograms/mouse) almost duplicated the animal life-span and total number of tumour cells decreased by 70-90%. Results suggest a major effect of DDB when administered in the lag phase of growth. DDB behaved as a very potent inhibitor of protein synthesis; consequently, ornithine decarboxylase activity (ODC, EC 4.1.1.17) is drastically reduced by DDB-treatment. | lld:pubmed |
| pubmed-article:8603376 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8603376 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8603376 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8603376 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8603376 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8603376 | pubmed:issn | 0304-3835 | lld:pubmed |
| pubmed-article:8603376 | pubmed:author | pubmed-author:MorataPP | lld:pubmed |
| pubmed-article:8603376 | pubmed:author | pubmed-author:UrdialesJ LJL | lld:pubmed |
| pubmed-article:8603376 | pubmed:author | pubmed-author:Sánchez-Jimén... | lld:pubmed |
| pubmed-article:8603376 | pubmed:author | pubmed-author:Núñez De... | lld:pubmed |
| pubmed-article:8603376 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8603376 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:8603376 | pubmed:volume | 102 | lld:pubmed |
| pubmed-article:8603376 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8603376 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8603376 | pubmed:pagination | 31-7 | lld:pubmed |
| pubmed-article:8603376 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8603376 | pubmed:meshHeading | pubmed-meshheading:8603376-... | lld:pubmed |
| pubmed-article:8603376 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8603376 | pubmed:articleTitle | Antiproliferative effect of dehydrodidemnin B (DDB), a depsipeptide isolated from Mediterranean tunicates. | lld:pubmed |
| pubmed-article:8603376 | pubmed:affiliation | Laboratorio de Bioquimica y Biologiá Molecular. Facultad de Ciencias. Universidad de Málaga, Spain. | lld:pubmed |
| pubmed-article:8603376 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8603376 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8603376 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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