| pubmed-article:8602887 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0014834 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0036536 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0036537 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0525009 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0392918 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0218633 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C0142292 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C1280519 | lld:lifeskim |
| pubmed-article:8602887 | lifeskim:mentions | umls-concept:C1522605 | lld:lifeskim |
| pubmed-article:8602887 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:8602887 | pubmed:dateCreated | 1996-5-7 | lld:pubmed |
| pubmed-article:8602887 | pubmed:abstractText | Synthesis of an artificial gene encoding the signal peptide of the Yersinia pestis capsule antigen (Caf1) was accomplished. A set of plasmids coding for hybrid proteins in which a modified sequence of the Caf1 signal peptide is connected to the amino acid sequence of the mature granulocyte-macrophage colony stimulating factor (GM-CSF) were constructed. Topography of the cleavage site of signal proteases was studied. The presence of an arginine residue within the N-terminal part of the mature human GM-CSF was shown to hinder the proper processing and translocation of the precursor through periplasmic membrane. A number of E. coli strains secreting biologically active mutants of human GM-CSF were obtained. | lld:pubmed |
| pubmed-article:8602887 | pubmed:language | rus | lld:pubmed |
| pubmed-article:8602887 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8602887 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8602887 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8602887 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8602887 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8602887 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8602887 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8602887 | pubmed:issn | 0132-3423 | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:AbramovV MVM | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:KriukovE AEA | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:KorobkoV GVG | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:Vul'fsonA NAN | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:IakimovS ASA | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:ShingarovaL... | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:AlibaevaR ARA | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:PetrovskaiaL... | lld:pubmed |
| pubmed-article:8602887 | pubmed:author | pubmed-author:GuzaevA AAA | lld:pubmed |
| pubmed-article:8602887 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8602887 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:8602887 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8602887 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8602887 | pubmed:pagination | 912-9 | lld:pubmed |
| pubmed-article:8602887 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:meshHeading | pubmed-meshheading:8602887-... | lld:pubmed |
| pubmed-article:8602887 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8602887 | pubmed:articleTitle | [Effect of the topography of the signal peptidase site on the effectiveness of secretion of recombinant human granulocyte-macrophage colony-stimulating factor into Escherichia coli periplasm]. | lld:pubmed |
| pubmed-article:8602887 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8602887 | pubmed:publicationType | English Abstract | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8602887 | lld:pubmed |
